TRPM7 抗体 (C-Term)
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- 抗原 See all TRPM7 抗体
- TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))
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抗原表位
- AA 1817-1863, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TRPM7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects TRPM7 at ~220 kDa. Shows no cross reactivity with TrpM6.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 产品特性
- Synonyms: CHAK1, LTRPC7, Transient receptor potential cation channel subfamily M member 7,Channel-kinase 1, Long transient receptor potential channel 7
- 纯化方法
- Protein G Chromatography
- 免疫原
- Fusion protein amino acids 1817-1863 (cytoplasmic C-terminus) of mouse TrpM7
- 克隆位点
- S74-25
- 亚型
- IgG1
- Top Product
- Discover our top product TRPM7 Primary Antibody
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anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 19-179) antibody
TRPM7 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibodyTRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (HRP)TRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 HRP
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (FITC)TRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 FITC
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Biotin)TRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 Biotin
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (PE)TRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 PE
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (APC)TRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 APC
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (PerCP)TRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 PerCP
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Atto 488)TRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 Atto 488
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Atto 594)TRPM7 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S74 Atto 594
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- 应用备注
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Western blot: 1-10 μg/mL (if results are off, try using the lysate without boiling). Immunoprecipitation. Immunocytochemistry: 0.1-1.0 μg/mL (Perox).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % Glycerol and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))
- 别名
- TRPM7 (TRPM7 产品)
- 别名
- cb495 antibody, TRPM7 antibody, chak antibody, chak1 antibody, ltrpc7 antibody, trp-plik antibody, ALSPDC antibody, CHAK antibody, CHAK1 antibody, LTRPC7 antibody, TRP-PLIK antibody, 2310022G15Rik antibody, 4833414K03Rik antibody, 5033407O22Rik antibody, LTrpC-7 antibody, Ltpr7 antibody, Ltrpc7 antibody, TRPPLIK antibody, Chak antibody, Trp-plik antibody, transient receptor potential cation channel subfamily M member 7 antibody, transient receptor potential cation channel, subfamily M, member 7 antibody, TRPM7 antibody, trpm7 antibody, Trpm7 antibody
- 背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligand- gated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants (3, 4).Synonyms: CHAK1, Channel-kinase 1, LTRPC7, Long transient receptor potential channel 7, Transient receptor potential cation channel subfamily M member 7
- 基因ID
- 58800
- UniProt
- Q923J1
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