KCNQ4 抗体 (AA 2-77)
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- 抗原 See all KCNQ4 抗体
- KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
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抗原表位
- AA 2-77
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KCNQ4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
- 特异性
- This antibody detects KCNQ4 K+ Channel at ~77 kDa.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat
- 产品特性
- Synonyms: KCNQ4, Voltage-gated potassium channel subunit Kv7.4, Potassium channel subunit alphaKvLQT4, KQT-like 4, Potassium voltage-gated channel subfamily KQT member 4
- 纯化方法
- Protein G chromatography
- 免疫原
- Fusion protein amino acid 2-77 of human KCNQ4 (Kv7. 4, KvLQT4)
- 克隆位点
- S43-6
- 亚型
- IgG1
- Top Product
- Discover our top product KCNQ4 Primary Antibody
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anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (C-Term) antibody
KCNQ4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 2-77) antibodyKCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) unconjugated
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 596-695) antibodyKCNQ4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 2-77) antibody (HRP)KCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) HRP
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 2-77) antibody (FITC)KCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) FITC
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 2-77) antibody (Alkaline Phosphatase (AP))KCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) Alkaline Phosphatase (AP)
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 2-77) antibody (Biotin)KCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) Biotin
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 2-77) antibody (PE)KCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) PE
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 2-77) antibody (APC)KCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) APC
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4) (AA 2-77) antibody (PerCP)KCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) PerCP
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- 应用备注
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Western blot: 1 - 10 μg/mL (if results are off, try using the lysate without boiling). Immunoprecipitation. Immunocytochemistry: 0.1 - 1.0 μg/mL (Perox).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol and 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
- 别名
- KCNQ4 (KCNQ4 产品)
- 别名
- KCNQ4 antibody, k(v)7.4 antibody, kv7.4 antibody, DFNA2 antibody, DFNA2A antibody, KV7.4 antibody, potassium voltage-gated channel subfamily Q member 4 antibody, potassium channel, voltage gated KQT-like subfamily Q, member 4 antibody, potassium voltage-gated channel, subfamily Q, member 4 antibody, KCNQ4 antibody, kcnq4 antibody, Kcnq4 antibody
- 背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). Specifically, the protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability (3), particularly in sensory cells of the cochlea (4). The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anticonvulsant drug (5).Synonyms: KCNQ4, KQT-like 4, Potassium channel subunit alpha KvLQT4, Potassium voltage-gated channel subfamily KQT member 4, Voltage-gated potassium channel subunit Kv7.4
- 基因ID
- 9132
- UniProt
- P56696
- 途径
- Sensory Perception of Sound
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