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CDK7 抗体 (C-Term)

CDK7 适用: 人 WB, IF, IP, IHC (fro), FACS 宿主: 小鼠 Monoclonal MO-1-1 unconjugated
产品编号 ABIN452138
发货至: 中国
  • 抗原 See all CDK7 抗体
    CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
    抗原表位
    • 32
    • 12
    • 7
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    • 1
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    C-Term
    适用
    • 98
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    • 6
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    • 2
    • 2
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    宿主
    • 80
    • 19
    • 1
    小鼠
    克隆类型
    • 74
    • 26
    单克隆
    标记
    • 53
    • 7
    • 5
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    This CDK7 antibody is un-conjugated
    应用范围
    • 74
    • 34
    • 33
    • 17
    • 15
    • 14
    • 14
    • 11
    • 8
    • 8
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    特异性
    Mo-1.1 recognizes the key cell cycle regulator cdk7, which is essential to activate the cdk2 kinase in G1 phase and the cdc2 kinase in G2/M phase.
    产品特性
    Synonyms: CAK1, P39 Mo15, STK1, CDK-activating kinase, Cell division protein kinase 7, TFIIH basaltranscription factor complex kinase subunit, 39 kDa protein kinase
    纯化方法
    Protein A affinity chromatography
    免疫原
    Recombinant C-terminal 221 aa fragment of human wild-type cdk7/CAK (cyclin activatingkinase)
    克隆位点
    MO-1-1
    亚型
    IgG2b
    Top Product
    Discover our top product CDK7 Primary Antibody
  • 应用备注
    Immunohistochemistry of frozen sections: 1/10 - 1/20, 1h at RT. Immunofluorescence. Immunoprecipitation of active kinase complex. Cell sorting (FACS analysis). Immunoblotting.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in 1 mL dist. water (final solution contains 0.09 % NaN3, 0.5 % BSA in PBS buffer, pH 7.4).
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
    别名
    CDK7 (CDK7 产品)
    别名
    CAK1 antibody, CDKN7 antibody, HCAK antibody, MO15 antibody, STK1 antibody, p39MO15 antibody, AI323415 antibody, AI528512 antibody, C230069N13 antibody, Cdkn7 antibody, Crk4 antibody, CD 7 antibody, CDK7 antibody, CG3319 antibody, DmCDK7 antibody, DmCdk7 antibody, DmMO15 antibody, DmMo15 antibody, Dmcdk7 antibody, Dmel\\CG3319 antibody, Mo15 antibody, cdk-7 antibody, cdk7 antibody, dCdk7 antibody, p40[MO15] antibody, p40MO15 antibody, stk1 antibody, zgc:85821 antibody, cak1 antibody, cdkn7 antibody, p39mo15 antibody, cyclin dependent kinase 7 antibody, cyclin-dependent kinase 7 antibody, Cyclin-dependent kinase 7 antibody, cyclin-dependent kinase 7 L homeolog antibody, CDK7 antibody, Cdk7 antibody, cdk7.L antibody, cdk7 antibody
    背景
    Cdk7 is a member of the cyclin dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. Cdk7 forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.Synonyms: 39 kDa protein kinase, CAK1, CDK-activating kinase, Cell division protein kinase 7, P39 Mo15, STK1, TFIIH basal transcription factor complex kinase subunit
    基因ID
    1022
    UniProt
    P50613
    途径
    Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
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