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Podoplanin 抗体 (Internal Region)

PDPN 适用: 人, 犬 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN401661
发货至: 中国
  • 抗原 See all Podoplanin (PDPN) 抗体
    Podoplanin (PDPN)
    抗原表位
    • 12
    • 11
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 77
    • 22
    • 4
    • 3
    • 1
    人, 犬
    宿主
    • 54
    • 24
    • 6
    • 5
    • 2
    • 2
    • 1
    山羊
    克隆类型
    • 49
    • 45
    多克隆
    标记
    • 52
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Podoplanin antibody is un-conjugated
    应用范围
    • 69
    • 33
    • 31
    • 24
    • 20
    • 16
    • 14
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is expected to recognize all isoforms (NP_006465.3, NP_938203.2, NP_001006625.1, NP_001006626.1).
    交叉反应 (详细)
    Species reactivity (expected):Canine.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence C-EKVDGDTQTTVEKD, from the internal region of the protein sequence
    Top Product
    Discover our top product PDPN Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit: 1/1000. Western blot: 1-3 μg/mL. Bands at approx 25 kDa and 35 kDa are detected in Human Brain (Cerebellum) lysates after1 μg/mL antibody staining.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    Podoplanin (PDPN)
    别名
    Podoplanin (PDPN 产品)
    别名
    PDPN antibody, AGGRUS antibody, GP36 antibody, GP40 antibody, Gp38 antibody, HT1A-1 antibody, OTS8 antibody, PA2.26 antibody, T1A antibody, T1A-2 antibody, OTS-8 antibody, RANDAM-2 antibody, T1-alpha antibody, T1a antibody, T1alpha antibody, E11 antibody, RTI40 antibody, podoplanin antibody, PDPN antibody, Pdpn antibody
    背景
    Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a Mr 38,000 membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha
    基因ID
    10630
    NCBI登录号
    NP_001006625
    UniProt
    Q86YL7
    途径
    Dicarboxylic Acid Transport
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