P2RX7 抗体 (N-Term)
-
- 抗原 See all P2RX7 抗体
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, 犬
-
宿主
- 山羊
-
克隆类型
- 多克隆
-
标记
- This P2RX7 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- YETNKVTRIQ SMNY-C
- 特异性
- This antibody recognizes P2X7 receptor.
- 交叉反应 (详细)
-
Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography
- 免疫原
- Peptide with sequence from the N-Terminus of the protein sequence (NP_002553.2). Genename: P2RX7
- Top Product
- Discover our top product P2RX7 Primary Antibody
-
-
- 应用备注
-
Peptide ELISA: 1/16000. Western blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 25, pp. E3265-73, (2015) (PubMed).
: "
-
Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 25, pp. E3265-73, (2015) (PubMed).
-
- 抗原
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- 别名
- P2RX7 / P2X7 (P2RX7 产品)
- 别名
- p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
- 背景
- The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.Synonyms: ATP receptor, P2X purinoceptor 7, P2Z receptor, Purinergic receptor
- 分子量
- 68.6kDa (NP_002553.2).
- 基因ID
- 5027
- NCBI登录号
- NP_002553
- UniProt
- Q99572
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
-