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P2RX7 抗体 (N-Term)

P2RX7 适用: 人, 小鼠, 大鼠, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN401660
发货至: 中国
  • 抗原 See all P2RX7 抗体
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    抗原表位
    • 15
    • 11
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 58
    • 40
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 57
    • 2
    • 2
    • 1
    山羊
    克隆类型
    • 58
    • 4
    多克隆
    标记
    • 28
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P2RX7 antibody is un-conjugated
    应用范围
    • 48
    • 26
    • 23
    • 13
    • 13
    • 12
    • 10
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    YETNKVTRIQ SMNY-C
    特异性
    This antibody recognizes P2X7 receptor.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography
    免疫原
    Peptide with sequence from the N-Terminus of the protein sequence (NP_002553.2). Genename: P2RX7
    Top Product
    Discover our top product P2RX7 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Graziano, Desdouits, Garzetti, Podini, Alfano, Rubartelli, Furlan, Benaroch, Poli: "Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 25, pp. E3265-73, (2015) (PubMed).

  • 抗原
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    别名
    P2RX7 / P2X7 (P2RX7 产品)
    别名
    p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
    背景
    The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.Synonyms: ATP receptor, P2X purinoceptor 7, P2Z receptor, Purinergic receptor
    分子量
    68.6kDa (NP_002553.2).
    基因ID
    5027
    NCBI登录号
    NP_002553
    UniProt
    Q99572
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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