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TRKB 抗体 (pTyr515)

Name: TRKB 抗体 (pTyr515)
SKU: ABIN401582
Availability: OutOfStock

NTRK2 适用: 人, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

Image no. 1 for anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (pTyr515) antibody (ABIN401582) (TRKB 抗体 (pTyr515))

1 image

产品编号 ABIN401582

发货至: 中国

Datasheet as PDF

抗原 See all TRKB (NTRK2) 抗体

TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
抗原表位
16

15

12

12

10

10

9

8

7

7

6

4

4

4

4

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr515
适用
133

89

86

6

6

5

4

3

3

1

1

1

1

1
人, 大鼠
宿主
138

7

4

1

1
兔
Compatible Secondaries
克隆类型
130

21
多克隆
标记
82

8

6

6

6

6

6

6

5

4

3

2

2

2

2

2

2

1
This TRKB antibody is un-conjugated
应用范围
107

53

50

21

19

18

15

14

7

5

3

2

1

1

1
Immunofluorescence (IF)

特异性

Antibody AP09481PU detects endogenous levels of TrkB only when phosphorylated at Tyrosine 515.

交叉反应（详细）

Species reactivity (tested):Human, Mouse and Rat

纯化方法

Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

免疫原

The antiserum was produced against synthesized phosphopeptide derived from Human TrkB around the phosphorylation site of Tyrosine 515 (P-Q-Y-pF-G).

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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 401-500) antibody
NTRK2 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (pTyr706) antibody
NTRK2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (pTyr516) antibody
NTRK2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 32-282) antibody
NTRK2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 207-339) antibody
NTRK2 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 10B6C4 unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 57-70), (Extracellular Domain) antibody
NTRK2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (pTyr817) antibody
NTRK2 适用: 人, 小鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 2A1 unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) antibody
NTRK2 适用: 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 1-477) antibody
NTRK2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (C-Term) antibody
NTRK2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunofluorescence: 1/100approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody (in aliquots) at-20 °C.
抗原

TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

别名

TrkB (NTRK2 产品)

别名

trkb antibody, trkb-b antibody, xtrkb antibody, si:ch211-220b11.1 antibody, trkB2 antibody, NTRK2 antibody, ntrk2 antibody, gp145-trkb antibody, TRKB antibody, GP145-TrkB antibody, trk-B antibody, AI848316 antibody, C030027L06Rik antibody, Tkrb antibody, trkB antibody, RATTRKB1 antibody, TRKB1 antibody, Trk-B antibody, TrkB antibody, neurotrophic receptor tyrosine kinase 2 antibody, neurotrophic receptor tyrosine kinase 2 L homeolog antibody, neurotrophic tyrosine kinase, receptor, type 2b antibody, neurotrophic receptor tyrosine kinase 2 S homeolog antibody, neurotrophic tyrosine kinase, receptor, type 2 antibody, NTRK2 antibody, ntrk2.L antibody, ntrk2b antibody, ntrk2.S antibody, ntrk2 antibody, Ntrk2 antibody

背景

Neurotrophins activate tyrosine kinase receptors of the Trk family (TrkA, TrkB and TrkC) and they all share a common low affinity receptor (p75NTR or p75). Although p75NTR does not appear to directly transduce NGF signals, this receptor appears to increase the responsiveness of the trk receptors and plays a role in the retrograde transport of neurotrophin signals from axon terminals to the cell body. The expression of trk gene neurotrophin receptors in mouse is tabulated by Barbacid (1994). NGF binds with high affinity and activates the TrkA tyrosine kinase receptor, which is apparently responsible for signal transduction. BDNF activates the TrkB tyrosine kinase receptor, which it shares with NT-4. NT-3 activates the TrkC tyrosine kinase receptor, but can also activate TrkA and TrkB receptors in certain cell systems. NT-4 primarily activates the TrkB tyrosine kinase receptor, which it shares with BDNF.Synonyms: BDNF/NT-3 growth factors receptor, GP145-TrkB, NTRK2, Neurotrophic tyrosine kinase receptor type 2, TRKB, TrkB tyrosine kinase

分子量

140 kDa

基因ID

4915

NCBI登录号

NP_001007098

UniProt

Q16620

途径

RTK signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport