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c-MYC 抗体 (pSer62)

Name: c-MYC 抗体 (pSer62)
SKU: ABIN401561
Availability: OutOfStock

MYC 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

Image no. 1 for anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody (ABIN401561) (c-MYC 抗体 (pSer62))

1 image

产品编号 ABIN401561

发货至: 中国

Datasheet as PDF

抗原 See all c-MYC (MYC) 抗体

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
抗原表位
55

45

44

40

24

21

19

16

15

11

10

7

7

6

6

6

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer62
适用
362

170

123

15

14

13

13

13

9

9

8

6

6

6

5

4

3

3

2

2

2

1

1

1

1

1
人, 小鼠, 大鼠
宿主
284

97

7

3

2

1
兔
Compatible Secondaries
克隆类型
275

118
多克隆
标记
196

31

25

25

9

9

9

9

9

9

8

7

5

5

5

5

5

3

2

2

2

2

2

2

2

1

1

1

1

1

1
This c-MYC antibody is un-conjugated
应用范围
293

142

91

83

80

64

58

28

26

17

14

13

12

11

7

4

2

1

1

1
Immunofluorescence (IF)

特异性

Antibody AP09470PU detects endogenous levels of Myc only when phosphorylated at Serine 62.

纯化方法

Immunoaffinity Chromatography using epitope-specific phosphopeptide.

免疫原

The antiserum was produced against synthesized phosphopeptide derived from human Myc around the phosphorylation site of Serine 62(P-L-Sp-P-S).

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anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody
MYC 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibody
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anti-Myc Proto-Oncogene protein (MYC) antibody
KO Validated MYC 适用: 人 WB, IF, ChIP 宿主: 兔 Monoclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) antibody
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应用备注

Immunofluorescence: 1/100approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody (in aliquots) at-20 °C.
抗原

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

别名

C-Myc (MYC 产品)

别名

MRTL antibody, MYCC antibody, bHLHe39 antibody, c-Myc antibody, CMYC antibody, c-myc antibody, C-MYC antibody, LOC100136746 antibody, ARC antibody, B430311C09Rik antibody, MYC antibody, NOP antibody, Nop30 antibody, RNCMYC antibody, mMyc antibody, AU016757 antibody, Myc2 antibody, Niard antibody, Nird antibody, cmyc antibody, zc-myc antibody, c-myc II antibody, myc-B antibody, myc2 antibody, myc1 antibody, CMyc antibody, zgc:55680 antibody, CG10798 antibody, D-Myc antibody, DM antibody, DMYc antibody, Dm antibody, Dmel\CG10798 antibody, Dmyc antibody, EG:BACN5I9.1 antibody, anon-WO03040301.171 antibody, bHLHe57 antibody, c-MYC antibody, d-myc antibody, dMYC antibody, dMyc antibody, dMyc1 antibody, da antibody, dm antibody, dm/dMyc antibody, dm/myc antibody, dmyc antibody, dmyc1 antibody, l(1)G0139 antibody, l(1)G0354 antibody, l(1)G0359 antibody, myc antibody, MYC proto-oncogene, bHLH transcription factor antibody, v-myc myelocytomatosis viral oncogene homolog antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, myelocytomatosis oncogene antibody, MYC proto-oncogene, bHLH transcription factor a antibody, MYC proto-oncogene, bHLH transcription factor L homeolog antibody, MYC proto-oncogene, bHLH transcription factor S homeolog antibody, v-myc myelocytomatosis viral oncogene homolog (avian) antibody, MYC proto-oncogene, bHLH transcription factor b antibody, CG10798 gene product from transcript CG10798-RB antibody, MYC antibody, LOC100136746 antibody, Nol3 antibody, Myc antibody, myca antibody, myc.L antibody, myc.S antibody, mycb antibody

背景

The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64

基因ID

4609

NCBI登录号

NP_002458

UniProt

P01106

途径

p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect