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STAT5A 抗体 (Tyr694)

STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401413
发货至: 中国
  • 抗原 See all STAT5A 抗体
    STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
    抗原表位
    • 40
    • 24
    • 17
    • 15
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    • 14
    • 9
    • 4
    • 4
    • 3
    • 3
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    • 1
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    Tyr694
    适用
    • 182
    • 101
    • 75
    • 25
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 168
    • 17
    • 2
    克隆类型
    • 156
    • 31
    多克隆
    标记
    • 109
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 1
    This STAT5A antibody is un-conjugated
    应用范围
    • 155
    • 68
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    • 40
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    • 29
    • 19
    • 18
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    • 10
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    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific for Stat5alpha protein phosphorylated at Y694.
    交叉反应 (详细)
    Species reactivity (expected):Rat, Human.
    Species reactivity (tested):Mouse.
    纯化方法
    Affinity chromatography
    免疫原
    synthetic peptide corresponding to residues surrounding Y694 of mouse STAT5alpha protein
    亚型
    IgG
    Top Product
    Discover our top product STAT5A Primary Antibody
  • 应用备注
    ELISA: 1/25,000. Western Blot: 1/500 - 1/2,000. Immunohistochemistry: 20 - 40 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.1 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
    别名
    STAT5 / STAT5A (STAT5A 产品)
    别名
    MGF antibody, STAT5 antibody, AA959963 antibody, Stat5 antibody, STAT5A/MGF antibody, STATA5 antibody, STAT5A antibody, stat5 antibody, stat5b antibody, signal transducer and activator of transcription 5A antibody, signal transducer and activator of transcription 5a antibody, STAT5A antibody, Stat5a antibody, stat5a antibody, LOC100348518 antibody, LOC100716811 antibody
    背景
    Signal trans-ducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic trans-cription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5alpha and Stat5beta. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus.Synonyms: MGF, Mammary gland factor, STAT-5, STAT-5A, Signal transducer and activator of transcription 5A
    基因ID
    20850
    NCBI登录号
    NP_035618
    UniProt
    P42230
    途径
    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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