This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain that mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins.Synonyms: ADP-ribosylation factor-binding protein GGA2, Gamma-adaptin-related protein 2, Golgi-localized gamma ear-containing ARF-binding protein 2, KIAA1080, VEAR, VHS domain and ear domain of gamma-adaptin