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GGA2 产品

(Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2))

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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008].

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Featured GGA2 Categories

GGA2 抗体

High quality antibodies with extensive validation data.

GGA2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GGA2 抗体

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Cat. No. ABIN3021665
Quantity 100 μL
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Reactivity Human, Mouse
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Cat. No. ABIN7255805
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Reactivity Rat
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  • (2)
Cat. No. ABIN1714802
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Recommended GGA2 ELISA试剂盒

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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6217475
Quantity 96 tests
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Recommended GGA2 蛋白

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Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3080727
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Reactivity Mouse
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Cat. No. ABIN3123611
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Latest Publications for our GGA2 Products

Kalthoff, Groos, Kohl, Mahrhold, Ungewickell: "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi." in: Molecular biology of the cell, Vol. 13, Issue 11, pp. 4060-73, (2002) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Nielsen, Madsen, Christensen, Nykjaer, Gliemann, Kasper, Pohlmann, Petersen: "The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein." in: The EMBO journal, Vol. 20, Issue 9, pp. 2180-90, (2001) (PubMed).

Puertollano, Aguilar, Gorshkova, Crouch, Bonifacino: "Sorting of mannose 6-phosphate receptors mediated by the GGAs." in: Science (New York, N.Y.), Vol. 292, Issue 5522, pp. 1712-6, (2001) (PubMed).

Hirst, Lui, Bright, Totty, Seaman, Robinson: "A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome." in: The Journal of cell biology, Vol. 149, Issue 1, pp. 67-80, (2000) (PubMed).

Synonyms and alternative names related to GGA2

golgi associated, gamma adaptin ear containing, ARF binding protein 2 (Gga2), golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), 1200007E24Rik, mKIAA1080, VEAR

Protein level used designations for GGA2

  • ADP-ribosylation factor-binding protein GGA2
  • gamma-adaptin-related protein 2
  • golgi-localized, gamma ear-containing, ARF-binding protein 2
  • VHS domain and ear domain of gamma-adaptin
  • VHS domain and ear domain-containing protein
  • golgi associated, gamma adaptin ear containing, ARF binding protein 2
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