ROBO1 抗体 (AA 1632-1644)
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- 抗原 See all ROBO1 抗体
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
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抗原表位
- AA 1632-1644
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ROBO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects ROBO-1.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat and Canine (100 %).
Species reactivity (tested):Human. - 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- Synthetic peptide corresponding to amino acids 1632-1644 of Human ROBO-1
- 亚型
- IgG
- Top Product
- Discover our top product ROBO1 Primary Antibody
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anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (Internal Region) antibody
Verified ROBO1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 1632-1644) antibodyROBO1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 1452-1651) antibodyROBO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-506), (Extracellular), (N-Term) antibodyROBO1 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 29-143) antibodyROBO1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-589) antibodyROBO1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (Internal Region) antibodyVerified ROBO1 适用: 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 1097-1130) antibodyROBO1 适用: 人 WB 宿主: 兔 Polyclonal RB54414 unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-589) antibodyROBO1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (Internal Region) antibodyROBO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/30,000-1/160,000. Western blot: 1/500-1/3,000 (Expect a band at approx. 181 kDa in size corresponding to ROBO-1). Immunohistochemistry on Paraffin Sections: 2-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- SStore the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
- 别名
- ROBO1 (ROBO1 产品)
- 别名
- DUTT1 antibody, SAX3 antibody, AW494633 antibody, AW742721 antibody, Gm310 antibody, ROBO1 antibody, dutt1 antibody, roundabout antibody, sax3 antibody, MGC122264 antibody, roundabout-1 antibody, roundabout guidance receptor 1 antibody, roundabout, axon guidance receptor, homolog 1 (Drosophila) antibody, roundabout guidance receptor 1 L homeolog antibody, ROBO1 antibody, Robo1 antibody, robo1 antibody, robo1.L antibody
- 背景
- ROBO-1 (also called Roundabout homolog 1 precursor and Deleted in U twenty twenty (DUTT)) functions as a receptor for SLIT1 and SLIT2. The SLIT proteins are thought to act as a molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. ROBO-1 may also be required for lung development. ROBO-1 is a type I membrane protein. ROBO-1 is a widely expressed protein with the exception of the kidney. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO-1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line. Multiple splice variants have been identified for this protein.Synonyms: DUTT1, Deleted in U Twenty Twenty, ROBO-1, Roundabout homolog 1
- 基因ID
- 6091
- NCBI登录号
- NP_002932
- UniProt
- Q9Y6N7
- 途径
- Positive Regulation of Endopeptidase Activity
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