ROBO1 抗体 (Internal Region)
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- 抗原 See all ROBO1 抗体
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ROBO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- ROBO1 Antibody detects endogenous levels of total ROBO1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ROBO1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ROBO1 Primary Antibody
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anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (Internal Region) antibody
Verified ROBO1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 1632-1644) antibodyROBO1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 1452-1651) antibodyROBO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-506), (Extracellular), (N-Term) antibodyROBO1 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 29-143) antibodyROBO1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-589) antibodyROBO1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (Internal Region) antibodyVerified ROBO1 适用: 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 1097-1130) antibodyROBO1 适用: 人 WB 宿主: 兔 Polyclonal RB54414 unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-589) antibodyROBO1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
- 别名
- ROBO1 (ROBO1 产品)
- 别名
- DUTT1 antibody, SAX3 antibody, AW494633 antibody, AW742721 antibody, Gm310 antibody, ROBO1 antibody, dutt1 antibody, roundabout antibody, sax3 antibody, MGC122264 antibody, roundabout-1 antibody, roundabout guidance receptor 1 antibody, roundabout, axon guidance receptor, homolog 1 (Drosophila) antibody, roundabout guidance receptor 1 L homeolog antibody, ROBO1 antibody, Robo1 antibody, robo1 antibody, robo1.L antibody
- 背景
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Description: Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development (PubMed:10102268, PubMed:24560577). Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1 (PubMed:24560577). In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its interaction with MYO9B, inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257). May be required for lung development (By similarity).
Gene: ROBO1
- 分子量
- 181 kDa
- 基因ID
- 6091
- UniProt
- Q9Y6N7
- 途径
- Positive Regulation of Endopeptidase Activity
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