FANCG 抗体 (N-Term)
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- 抗原 See all FANCG 抗体
- FANCG (Fanconi Anemia Complementation Group G (FANCG))
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抗原表位
- AA 1-12, N-Term
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适用
- 人, Chimpanzee
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FANCG antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is directed against FANCG protein.
- 交叉反应 （详细）
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Species reactivity (expected):Chimpanzee (100 %).
Species reactivity (tested):Human. - 纯化方法
- Immunoaffinity Chromatography.
- 免疫原
- Synthetic peptide corresponding to amino acids 1-12 of human FANCG protein
- 亚型
- IgG
- Top Product
- Discover our top product FANCG Primary Antibody
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anti-Fanconi Anemia Complementation Group G (FANCG) (AA 1-622) antibody
FANCG 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (C-Term) antibodyVerified FANCG 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 1-622) antibodyFANCG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (Center) antibodyFANCG 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (pSer383) antibodyFANCG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 1-12) antibodyFANCG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 343-622) antibodyFANCG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 1-622) antibodyFANCG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (pSer383) antibodyFANCG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10,000-1/50,000. Western blot: 1/500-1/2,000 (Expect a band approximately 69 kDa in size corresponding toFANCG in the appropriate human tissue). Immunohistochemistry on Paraffin Sections: 1/500-1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.93 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- FANCG (Fanconi Anemia Complementation Group G (FANCG))
- 别名
- XRCC9 / FANCG (FANCG 产品)
- 别名
- xFANCG antibody, FAG antibody, XRCC9 antibody, AU041407 antibody, Xrcc9 antibody, Fanconi anemia complementation group G S homeolog antibody, Fanconi anemia complementation group G antibody, Fanconi anemia, complementation group G antibody, fancg.S antibody, FANCG antibody, Fancg antibody
- 背景
- FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies caused by defects in the FANCG gene. At the cellular level it is associated with hypersensitivity to DNAdamaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.Synonyms: DNA repair protein XRCC9, FACG, Fanconi anemia group G protein
- 分子量
- 68.6 kDa
- 基因ID
- 2189
- NCBI登录号
- NP_004620
- UniProt
- O15287
- 途径
- DNA Damage Repair
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