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ATF3 抗体 (AA 113-130)

ATF3 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401262
发货至: 中国
  • 抗原 See all ATF3 抗体
    ATF3 (Activating Transcription Factor 3 (ATF3))
    抗原表位
    • 16
    • 14
    • 10
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 113-130
    适用
    • 63
    • 27
    • 25
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 56
    • 8
    克隆类型
    • 56
    • 8
    多克隆
    标记
    • 35
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATF3 antibody is un-conjugated
    应用范围
    • 56
    • 29
    • 29
    • 15
    • 13
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is directed against ATF3 and is useful in determining its presence in various assays including ELISA and western blotting. It recognizes over-expressed ATF3 protein found in various expression systems.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    亚型
    IgG
    Top Product
    Discover our top product ATF3 Primary Antibody
  • 应用备注
    ELISA: 1: 5,000 to 1: 20,000. Western blot: 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ATF3 (Activating Transcription Factor 3 (ATF3))
    别名
    ATF3 (ATF3 产品)
    别名
    zgc:55526 antibody, ATF3 antibody, LRG-21 antibody, LRF-1 antibody, LRFI antibody, atf-3 antibody, activating transcription factor 3 antibody, activating transcription factor 3 L homeolog antibody, atf3 antibody, ATF3 antibody, Atf3 antibody, atf3.L antibody
    背景
    ATF3, or Activating Transcription Factor 3, is a member of mammalian activation TF/CREB protein family of transcription factors. ATF3 binds the cAMP response element (cre) (consensus: 5'-gtgacgt[ac][ag]-3'), a sequence present in many viral and cellular promoters. However, ATF3 represses rather than activates transcription from promoters with ATF sites stabilizing inhibitory co-factors at the promoter. Alternate splicing forms of ATF3, called ATF3 delta Zip, lack the leucine zipper domain and do not bind DNA. ATF3 delta Zip stimulates transcription, presumably by sequestering inhibitory co-factors away from the promoter. Human ATF3 is a 20575 Da protein composed of 181 amino acids.Synonyms: ATF-3, Activating transcription factor 3, Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3
    基因ID
    467
    NCBI登录号
    NP_001025458
    UniProt
    P18847
    途径
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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