Keratin 7/17 抗体
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- 抗原 See all Keratin 7/17 (KRT7/17) 抗体
- Keratin 7/17 (KRT7/17)
- 适用
- 人, Cow, Pig
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Keratin 7/17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Recognizes a unique epitope shared by the intermediate filament keratins, cytokeratin 7 and cytokeratin 17, a 54kD type II basic cytokeratin, and 46kD type I acidic cytokeratin respectively. Cytokeratins are located in the intracytoplasmic cytoskeleton of epithelial tissues and their neoplasms, including the lungs, ovary and breast. Each keratin filament consists of at least one type I and one type II keratin chain, which then assemble to form a cytoskeletal network, extending from the surface of the nucleus to the cell membrane. The expression of a particular type of cytokeratin depends mainly on the type of epithelium and the development stage of the cell, including its corresponding malignant state. Immunohistochemical analysis of cytokeratin profiles is therefore a valuable tool for diagnosis and characterization, and this particular antibody could be useful for the evaluation of some stratified epithelia which express cytokeratin 17, but not cytokeratin 7. Reported as suitable for use in immunocytochemistry.
- 无交叉反应
- 小鼠, 兔, 大鼠
- 纯化方法
- Affinity purified
- 免疫原
- HeLa cell cytoskeleton preparation.
- 克隆位点
- C-46
- 亚型
- IgG1
- Top Product
- Discover our top product KRT7/17 Primary Antibody
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anti-Keratin 7/17 (KRT7/17) antibody
KRT7/17 适用: 人, Cow, Pig WB, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal C-46 unconjugated
anti-Keratin 7/17 (KRT7/17) antibodyKRT7/17 适用: 人, Cow WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal C-46 unconjugated
anti-Keratin 7/17 (KRT7/17) antibodyKRT7/17 适用: 人, Cow, Pig WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
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- 应用备注
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Approved: IHC, IHC-P (20 - 30 μg/mL), IP, WB (2 - 3 μg/mL)
Usage: Western Blot: LS-C58267 detects bands of approximately 54kD and 46kD in HeLa cytoskeleton cell lysates under reducing conditions. Immunohistology: This product requires protein digestion pre-treatment of paraffin sections using pepsin prior to staining. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Short term: -20°C
Long term: -20°C.
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- 抗原
- Keratin 7/17 (KRT7/17)
- 别名
- Cytokeratin 7+17 (KRT7/17 产品)
- 别名
- KRT7 antibody, CK7 antibody, keratin 7 antibody, KRT7 antibody
- 背景
- This antibody detects: Cytokeratin 7+17
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