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- 抗原 See all PTPRA 抗体
- PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))
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抗原表位
- AA 89-120, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPRA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PTP alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-120 amino acids from the N-terminal region of human PTP alpha.
- 克隆位点
- RB0549
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PTPRA Primary Antibody
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anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) (AA 20-142) antibody
PTPRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) antibodyPTPRA 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) (Cytoplasmic Domain) antibodyPTPRA 适用: 人, 小鼠, 犬, Cow, Pig, 猴, 兔, 马, Bat, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) (Cytoplasmic Domain) antibodyPTPRA 适用: 人, 小鼠, 大鼠, 犬, 小鸡, Cow, Pig, 猴, 兔, 斑马鱼, 马, Bat, Hamster, 非洲爪蟾 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) (Extracellular Domain) antibodyPTPRA 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) (AA 151-250) antibodyPTPRA 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) (AA 20-142) antibodyPTPRA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) (N-Term) antibodyPTPRA 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) (AA 618-796) antibodyPTPRA 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) antibodyPTPRA 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))
- 别名
- PTP alpha (PTPRA 产品)
- 别名
- PTPRA antibody, heptp antibody, hlpr antibody, hptpa antibody, hptpalpha antibody, lrp antibody, ptpa antibody, ptprl2 antibody, r-ptp-alpha antibody, rptpa antibody, HEPTP antibody, HLPR antibody, HPTPA antibody, HPTPalpha antibody, LRP antibody, PTPA antibody, PTPRL2 antibody, R-PTP-alpha antibody, RPTPA antibody, Ptpa antibody, Ptpalpha antibody, Rptpalpha antibody, Rptra antibody, Rptralpha antibody, RPTP[a] antibody, zf-RPTP[a] antibody, ptpa-a antibody, protein tyrosine phosphatase, receptor type A antibody, protein tyrosine phosphatase, receptor type, A antibody, protein tyrosine phosphatase, receptor type A S homeolog antibody, PTPRA antibody, ptpra antibody, Ptpra antibody, ptpra.S antibody
- 背景
- Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases. Coordinated control of kinases and phosphatases provides the cell with the capacity to rapidly switch between phosphorylated and dephosphorylated protein states in dynamic response to environmental stimuli. Activation of critical enzymes by kinase phosphorylation alone is not enough to provide adequate regulation ?it is the combination with phosphatase dephosphorylation that effectively creates on/off switches to control cellular events. Errors in control, either through kinases or their counterpart phosphatases, can lead to unchecked cell growth attributable to human cancers and developmental disorders. Potential mechanisms to control dephosphorylation include changes in the expression of protein phosphatases, their subcellular localization, phosphorylation of phosphatase catalytic and regulatory subunits and regulation by endogenous phosphatase inhibitors. Most protein phosphatases are not stringently specific for their substrates. Consequently, changes in phosphatase activity may have a broad impact on dephosphorylation and turnover of phosphoproteins that are substrates for different kinases. This may be an important point of control to connect cellular circuitry of interrelated signaling pathways, and to synchronize physiological responses.
- 分子量
- 90719
- 基因ID
- 5786
- NCBI登录号
- NP_002827, NP_543030, NP_543031
- UniProt
- P18433
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