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- 抗原 See all RPS6KB2 抗体
- RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))
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抗原表位
- AA 452-482, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RPS6KB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This p70 S6Kbeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human p70 S6Kbeta.
- 克隆位点
- RB0891
- 亚型
- Ig Fraction
- Top Product
- Discover our top product RPS6KB2 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex." in: Journal of pharmacological sciences, Vol. 134, Issue 4, pp. 197-202, (2018) (PubMed).
: "Regulatory effects of SKAR in interferon ? signaling and its role in the generation of type I IFN responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 31, pp. 11377-82, (2014) (PubMed).
: "S6 kinase 2 potentiates interleukin-3-driven cell proliferation." in: Journal of leukocyte biology, Vol. 78, Issue 6, pp. 1378-85, (2005) (PubMed).
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The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex." in: Journal of pharmacological sciences, Vol. 134, Issue 4, pp. 197-202, (2018) (PubMed).
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- 抗原
- RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))
- 别名
- p70 S6Kbeta (RPS6KB2 产品)
- 别名
- KLS antibody, P70-beta antibody, P70-beta-1 antibody, P70-beta-2 antibody, S6K-beta2 antibody, S6K2 antibody, SRK antibody, STK14B antibody, p70(S6K)-beta antibody, p70S6Kb antibody, 70kDa antibody, ribosomal protein S6 kinase B2 antibody, ribosomal protein S6 kinase, polypeptide 2 antibody, RPS6KB2 antibody, Rps6kb2 antibody
- 背景
- This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
- 分子量
- 53455
- 基因ID
- 6199
- NCBI登录号
- NP_003943
- UniProt
- Q9UBS0
- 途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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