MAPK10 抗体 (N-Term)
(1 reference)Quick Overview for MAPK10 抗体 (N-Term) (ABIN391727)
抗原
See all MAPK10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This MAPK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAPK10.
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亚型
- Ig Fraction
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anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 175-464) antibody
MAPK10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 180-329) antibodyMAPK10 适用: 人, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal 2B10H12 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 88-332) antibodyMAPK10 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 28-233) antibodyMAPK10 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 10E4A4 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 180-329) antibodyMAPK10 适用: 人, 大鼠 宿主: 小鼠 Monoclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) antibodyMAPK10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 1-319) antibodyMAPK10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E12-1F7 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) antibodyMAPK10 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) antibodyMAPK10 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 8A5D11 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 25-74) antibodyMAPK10 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4201-12, (2008) (PubMed).
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: "Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4201-12, (2008) (PubMed).
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- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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别名
- JNK3
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背景
- JNK3 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.
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分子量
- 52585
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基因ID
- 5602
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NCBI登录号
- NP_002744, NP_620446, NP_620447, NP_620448
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UniProt
- P53779
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途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
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