MAPK10 抗体 (C-Term)
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- 抗原 See all MAPK10 抗体
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAPK10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- JNK3 Antibody detects endogenous levels of total JNK3.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human MAPK10, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product MAPK10 Primary Antibody
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anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 175-464) antibody
MAPK10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 180-329) antibodyMAPK10 适用: 人, 大鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2B10H12 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 88-332) antibodyMAPK10 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) antibodyMAPK10 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 8A5D11 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 28-233) antibodyMAPK10 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 10E4A4 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) antibodyMAPK10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 1-319) antibodyMAPK10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E12-1F7 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 25-74) antibodyMAPK10 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 山羊, 豚鼠, 马, 兔, 非洲爪蟾, 猴, Bat, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 1-30), (N-Term) antibodyMAPK10 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01017 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 1-30) antibodyMAPK10 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
- 别名
- MAPK10 (MAPK10 产品)
- 别名
- MAPK10 antibody, zgc:123234 antibody, DKFZp459H0638 antibody, Jnk3 antibody, SAPKC antibody, SAPb antibody, Serk2 antibody, JNK3 antibody, JNK3A antibody, PRKM10 antibody, SAPK1b antibody, p493F12 antibody, p54bSAPK antibody, C230008H04Rik antibody, JNK3B1 antibody, JNK3B2 antibody, SAPK(beta) antibody, ATMPK10 antibody, MAP kinase 10 antibody, mitogen-activated protein kinase 8 S homeolog antibody, mitogen-activated protein kinase 10 antibody, mitogen activated protein kinase 10 antibody, MAP kinase 10 antibody, mapk8.S antibody, MAPK10 antibody, mapk10 antibody, Mapk10 antibody, MPK10 antibody
- 背景
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Description: Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3. In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. Plays regulatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtubule regulator STMN2. Acts in the regulation of the amyloid-beta precursor protein/APP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the photic regulation of the circadian clock (PubMed:22441692).
Gene: MAPK10
- 分子量
- 48 kDa
- 基因ID
- 5602
- UniProt
- P53779
- 途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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