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c-Rel 抗体 (C-Term)

This anti-c-Rel antibody is a 兔 多克隆 antibody detecting c-Rel in WB. Suitable for 人 和 小鼠.
产品编号 ABIN390316
发货至: 中国

Quick Overview for c-Rel 抗体 (C-Term) (ABIN390316)

抗原

See all c-Rel 抗体
c-Rel (REL proto-oncogene (c-Rel))

适用

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  • 1
  • 1
人, 小鼠

宿主

  • 74
  • 9
  • 1

克隆类型

  • 67
  • 17
多克隆

标记

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This c-Rel antibody is un-conjugated

应用范围

  • 57
  • 33
  • 13
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  • 8
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  • 3
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB8325
  • 抗原表位

    • 23
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    AA 586-619, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This C-rel (NFkB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-619 amino acids from the C-terminal region of human C-rel (NFkB).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    c-Rel (REL proto-oncogene (c-Rel))

    别名

    C-rel (NFkB)

    背景

    Nuclear factor (NF)-kappa B is a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NF-kB regulates the expression of a wide variety of genes that involved in apoptosis, viral life cycle, tumorigenesis, autoimmune diseases and inflammation. NF-kB is a heterodimer of members of the rel family of proteins such as p50, p65, and c-rel. In most cells, inhibitory IkB proteins sequester NF-kB/Rel in the cytoplasm. Cellular stimulation precipitates degradation of IkB and modification of NF-kB/Rel proteins, permitting translocation of NF-kB/Rel (c-Rel and RelA) to the nucleus for action on target genes. The important role of c-Rel in B-cell development, growth, and survival has been intensively studied, as well as its function in differentiation and lymphopoiesis (particularly lymphoid cancer).

    分子量

    68520

    基因ID

    5966

    NCBI登录号

    NP_002899

    UniProt

    Q04864
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