c-Rel 抗体 (C-Term)
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Quick Overview for c-Rel 抗体 (C-Term) (ABIN390316)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 586-619, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This C-rel (NFkB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-619 amino acids from the C-terminal region of human C-rel (NFkB).
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亚型
- Ig Fraction
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anti-REL proto-oncogene (c-Rel) (pSer503) antibody
c-Rel 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) antibodyc-Rel 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) antibodyc-Rel 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-REL proto-oncogene (c-Rel) (AA 1-300) antibodyc-Rel 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (AA 268-306), (Middle Region) antibodyc-Rel 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (Internal Region) antibodyVerified c-Rel 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) antibodyc-Rel 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 8C2 unconjugated
anti-REL proto-oncogene (c-Rel) (C-Term) antibodyc-Rel 适用: 人, 犬, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (Thr69) antibodyc-Rel 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- c-Rel (REL proto-oncogene (c-Rel))
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别名
- C-rel (NFkB)
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背景
- Nuclear factor (NF)-kappa B is a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NF-kB regulates the expression of a wide variety of genes that involved in apoptosis, viral life cycle, tumorigenesis, autoimmune diseases and inflammation. NF-kB is a heterodimer of members of the rel family of proteins such as p50, p65, and c-rel. In most cells, inhibitory IkB proteins sequester NF-kB/Rel in the cytoplasm. Cellular stimulation precipitates degradation of IkB and modification of NF-kB/Rel proteins, permitting translocation of NF-kB/Rel (c-Rel and RelA) to the nucleus for action on target genes. The important role of c-Rel in B-cell development, growth, and survival has been intensively studied, as well as its function in differentiation and lymphopoiesis (particularly lymphoid cancer).
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分子量
- 68520
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基因ID
- 5966
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NCBI登录号
- NP_002899
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UniProt
- Q04864
抗原
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