电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

OAS1 抗体 (C-Term)

OAS1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1937 unconjugated
产品编号 ABIN390164
发货至: 中国
  • 抗原 See all OAS1 抗体
    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
    抗原表位
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 302-330, C-Term
    适用
    • 56
    • 35
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    人, 小鼠
    宿主
    • 54
    • 3
    • 1
    克隆类型
    • 55
    • 3
    多克隆
    标记
    • 28
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OAS1 antibody is un-conjugated
    应用范围
    • 33
    • 23
    • 18
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This OAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human OAS1.
    克隆位点
    RB1937
    亚型
    Ig Fraction
    Top Product
    Discover our top product OAS1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Gielen, Johnston, Edwards: "Azithromycin induces anti-viral responses in bronchial epithelial cells." in: The European respiratory journal, Vol. 36, Issue 3, pp. 646-54, (2010) (PubMed).

    Kriegs, Bürckstümmer, Himmelsbach, Bruns, Frelin, Ahlén, Sällberg, Hildt: "The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28343-51, (2009) (PubMed).

    Wang, Ghosh, Baigude, Yang, Qiu, Xia, Zhou, Rana, Xu: "Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15845-52, (2008) (PubMed).

    Han, Townsend, Jha, Paranjape, Silverman, Barton: "A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L." in: Journal of virology, Vol. 81, Issue 11, pp. 5561-72, (2007) (PubMed).

    Alimirah, Chen, Davis, Choubey: "IFI16 in human prostate cancer." in: Molecular cancer research : MCR, Vol. 5, Issue 3, pp. 251-9, (2007) (PubMed).

    van den Pol, Robek, Ghosh, Ozduman, Bandi, Whim, Wollmann: "Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain." in: Journal of virology, Vol. 81, Issue 1, pp. 332-48, (2006) (PubMed).

    Lee, Wu, Lee, Chuang, Katakura, Liu, Chan, Tawatao, Chung, Shen, Cottam, Lai, Raz, Carson: "Activation of anti-hepatitis C virus responses via Toll-like receptor 7." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 6, pp. 1828-33, (2006) (PubMed).

  • 抗原
    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
    别名
    OAS1 (OAS1 产品)
    别名
    OAS1 antibody, IFI-4 antibody, OIAS antibody, OIASI antibody, L3 antibody, Pp2a2 antibody, 2',5'-oligoadenylate synthetase 1 antibody, 2'-5'-oligoadenylate synthetase 1 antibody, 2'-5' oligoadenylate synthetase 1A antibody, protein phosphatase 2 catalytic subunit beta antibody, OAS1 antibody, Oas1a antibody, Ppp2cb antibody, Oas1 antibody
    背景
    OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
    分子量
    46029
    基因ID
    4938
    NCBI登录号
    NP_001027581, NP_002525, NP_058132
    UniProt
    P00973
    途径
    Hepatitis C
You are here:
客服