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OAS1 抗体 (Middle Region)

Name: OAS1 抗体 (Middle Region)
SKU: ABIN2773987
Availability: OutOfStock

OAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-OAS1 antibody (ARP51359_P050) (OAS1 抗体 (Middle Region))

IHC

WB Suggested Anti-OAS1 Antibody Titration: 0. (OAS1 抗体 (Middle Region))

Host: Rabbit Target Name: OAS1 Sample Tissue: Human Hela Antibody Dilution: 1. (OAS1 抗体 (Middle Region))

3 images

(2 references)

产品编号 ABIN2773987

发货至: 中国

Datasheet as PDF

抗原 See all OAS1 抗体

OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
抗原表位
7

6

5

3

2

2

2

1

1

1

1

1

1

1
Middle Region

适用

人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 豚鼠
宿主
54

3

1
兔
Compatible Secondaries
克隆类型
55

3
多克隆
标记
28

6

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1
This OAS1 antibody is un-conjugated
应用范围
33

22

18

11

7

5

4

3

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

RRQLTKPRPV ILDPADPTGN LGGGDPKGWR QLAQEAEAWL NYPCFKNWDG

预测反应

Cow: 93%, Dog: 93%, Guinea Pig: 87%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

产品特性

This is a rabbit polyclonal antibody against OAS1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human OAS1

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anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibody
OAS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 139-358) antibody
OAS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibody
OAS1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 302-330), (C-Term) antibody
OAS1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1937 unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibody
OAS1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 296-395) antibody
OAS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-364) antibody
OAS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) antibody
OAS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibody
OAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 324-373) antibody
OAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 414 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Yu, Yan, Liu, Li, Liu, Zhu, Chen, Han: "Pattern recognition receptor-initiated innate antiviral response in mouse adipose cells." in: Immunology and cell biology, Vol. 92, Issue 2, pp. 105-15, (2014) (PubMed).

Zhu, Chen, Yan, Liu, Li, Zhang, Yu, Chen, Han: "RIG-I-like receptors mediate innate antiviral response in mouse testis." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1455-67, (2013) (PubMed).
抗原

OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

别名

OAS1 (OAS1 产品)

别名

OAS1 antibody, IFI-4 antibody, OIAS antibody, OIASI antibody, L3 antibody, Pp2a2 antibody, 2',5'-oligoadenylate synthetase 1 antibody, 2'-5'-oligoadenylate synthetase 1 antibody, 2'-5' oligoadenylate synthetase 1A antibody, protein phosphatase 2 catalytic subunit beta antibody, OAS1 antibody, Oas1a antibody, Ppp2cb antibody, Oas1 antibody

背景

This protein is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: IFI-4, OIAS, OIASI
Protein Interaction Partner: EXOC5, TRIM27, ACTN1, PRMT6, WBSCR22, RPL30, HCVgp1,
Protein Size: 414

分子量

47 kDa

基因ID

4938

NCBI登录号

NM_001032409, NP_001027581

途径

Hepatitis C