c-MET 抗体 (pTyr1234, pTyr1235)
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北京 101111
Quick Overview for c-MET 抗体 (pTyr1234, pTyr1235) (ABIN387740)
抗原
See all c-MET (MET) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pTyr1234, pTyr1235
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This monoclonal antibody is generated from mice immunized with a KLH conjugated synthetic peptide corresponding to sequences in Tyr1234/1235 region of human Met and residues both Tyr1234 and Tyr1235 are phosphorylated.
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亚型
- IgG1
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应用备注
- WB: 1:100~500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- c-MET (MET) (Met Proto-Oncogene (MET))
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别名
- MET/HGFR
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背景
- The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 155541
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基因ID
- 4233
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NCBI登录号
- NP_000236, NP_001120972
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UniProt
- P08581
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途径
- RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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