GSK3 alpha 抗体 (N-Term) (Sepharose)
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- 抗原 See all GSK3 alpha (GSK3a) 抗体
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GSK3 alpha antibody is conjugated to Sepharose
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 特异性
- Human/Mouse GSK-3α
- 产品特性
- Mouse Anti-GSK-3a-SEPH
- 纯化方法
- Purified
- 免疫原
- Recombinant N-terminal GSK-3alpha
- 克隆位点
- SBGSK3a4
- 亚型
- IgG2a
- Top Product
- Discover our top product GSK3a Primary Antibody
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- 应用备注
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- Applications: WB - Quality tested , IP - Quality tested
- Working Dilutions: Immunoblotting Purified (UNLB) antibody ≤ 2 g/mL HRP conjugate 1:2,000 - 1:5,000 Immunoprecipitation Purified (UNLB) antibody 5 g SEPH conjugate 40 L
- 限制
- 仅限研究用
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- 缓冲液
- 50 tests in 2.0 mL of borate buffered saline, pH 8.2. No preservatives or amine- containing buffer salts added
- 储存液
- Without preservative
- 注意事项
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C
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- 抗原
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
- 别名
- GSK-3a (GSK3a 产品)
- 别名
- 2700086H06Rik antibody, GSK3A antibody, GSK-3[a] antibody, GSK-3[b] antibody, GSK3 antibody, gsk3a antibody, xgsk3 antibody, glycogen synthase kinase 3 alpha antibody, glycogen synthase kinase 3 alpha b antibody, glycogen synthase kinase 3 alpha S homeolog antibody, GSK3A antibody, Gsk3a antibody, gsk3a antibody, gsk3ab antibody, gsk3a.S antibody, Bm1_31380 antibody
- 背景
- Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3 α and GSK-3β. The two isoforms share 97 % sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.
- 途径
- PI3K-Akt Signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
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