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TIMP4 抗体 (HRP)

TIMP4 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal SB30c HRP
产品编号 ABIN375479
发货至: 中国
  • 抗原 See all TIMP4 抗体
    TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))
    适用
    • 68
    • 37
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    宿主
    • 87
    • 10
    小鼠
    克隆类型
    • 87
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    单克隆
    标记
    • 38
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    • 2
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    • 2
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    This TIMP4 antibody is conjugated to HRP
    应用范围
    • 77
    • 45
    • 40
    • 13
    • 13
    • 11
    • 9
    • 8
    • 8
    • 6
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    The antibody detects: Human TIMP-4
    To insure lot-to-lot consistency, each batch of product is tested by IHC to conform with the characteristics of a standard reference reagent.
    纯化方法
    Purified
    免疫原
    Recombinant TIMP-4
    克隆位点
    SB30c
    亚型
    IgG2a
    Top Product
    Discover our top product TIMP4 Primary Antibody
  • 应用备注
    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    样本量
    1 mL
    限制
    仅限研究用
  • 状态
    Liquid
    注意事项
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
  • 抗原
    TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))
    别名
    TIMP-4 (TIMP4 产品)
    别名
    TIMP4 antibody, TIMP-4 antibody, timp4 antibody, TIMP metallopeptidase inhibitor 4 antibody, TIMP metallopeptidase inhibitor 4, tandem duplicate 3 antibody, tissue inhibitor of metalloproteinase 4 antibody, TIMP4 antibody, timp4.3 antibody, Timp4 antibody
    背景
    Tissue inhibitors of matrix metalloproteinases (TIMPs) constitute a family of secreted multifunctional proteins which are classified based on structural similarity to each other as well as their ability to inhibit matrix metalloproteinases (MMPs). TIMPs therefore play a critical role in ECM homeostasis but have also been shown to have erythroid-potentiating and cell growth-promoting activities. TIMP-4 (approx. 23 kDa), unlike TIMP-1, TIMP-2 and TIMP-3, shows restricted localization to cardiac, neural, breast and muscle tissue. Cardiospecific TIMP-4 seems to play a significant role in regulating the normal cell phenotype since reduced levels elicit cellular transformation. It has been shown to be an inhibitor of MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9 with a preference for MMP-2 and MMP-7.
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