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ERCC1 抗体 (N-Term)

ERCC1 适用: 人 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375196
发货至: 中国
  • 抗原 See all ERCC1 抗体
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    抗原表位
    • 15
    • 11
    • 10
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 80
    • 38
    • 24
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 55
    • 23
    • 2
    山羊
    克隆类型
    • 56
    • 24
    多克隆
    标记
    • 52
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERCC1 antibody is un-conjugated
    应用范围
    • 73
    • 44
    • 15
    • 13
    • 13
    • 10
    • 10
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to ERCC1.
    纯化方法
    Ammonium sulphate precipitation followed by antigen affinity chromatography
    免疫原
    Peptide with sequence DPGKDKEGVPQPS-C, from the N Terminus of the protein sequence
    Top Product
    Discover our top product ERCC1 Primary Antibody
  • 应用备注
    ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    别名
    ERCC1 (ERCC1 产品)
    别名
    COFS4 antibody, RAD10 antibody, UV20 antibody, Ercc-1 antibody, ercc1 antibody, T12H1.18 antibody, T12H1_18 antibody, UV REPAIR DEFICIENT 7 antibody, UVR7 antibody, ERCC excision repair 1, endonuclease non-catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 1 antibody, DNA excision repair protein ERCC-1 antibody, nucleotide repair protein antibody, excision repair cross-complementation group 1 L homeolog antibody, excision repair cross-complementation group 1 antibody, ERCC1 antibody, Ercc1 antibody, CC1G_04546 antibody, CpipJ_CPIJ013903 antibody, PITG_13719 antibody, ercc1 antibody, ercc1.L antibody
    背景
    The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1 XPF complex makes the 5'incision. Elevated levels of ERCC1 have also been reported in Cisplatin resistant cells.Synonyms: COFS4, DNA excision repair protein ERCC-1, UV20
    基因ID
    2067
    NCBI登录号
    NP_001974
    UniProt
    P07992
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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