CHRNA4 抗体 (Internal Region)
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- 抗原 See all CHRNA4 抗体
- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
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抗原表位
- AA 29-43, Internal Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This CHRNA4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 序列
- C-HVETRAHAEE RLLKK
- 特异性
- This antibody recognizes CHRNA4 (aa29-43). This antibody is expected Not to cross-react with the similar alpha 2 subunit.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Bovine, Canine.
Species reactivity (tested):Human, Rat. - 纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- 免疫原
- Syntehtic peptide from the internal region of Human CHRNA4 (NP_000735.1) Genename: CHRNA4
- Top Product
- Discover our top product CHRNA4 Primary Antibody
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anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 49-242) antibody
CHRNA4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 29-242) antibodyCHRNA4 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7B4H1 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 531-627) antibodyCHRNA4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 176-208) antibodyCHRNA4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53684 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 472-503) antibodyCHRNA4 适用: 人 WB 宿主: 兔 Polyclonal RB53481 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) antibodyCHRNA4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (N-Term) antibodyCHRNA4 适用: 人, Cow, 豚鼠, 兔, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) antibodyCHRNA4 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) antibodyCHRNA4 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 1-451) antibodyCHRNA4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/64000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
- 别名
- Neuronal Acetylcholine Receptor Subunit alpha-4 (CHRNA4 产品)
- 别名
- NACHRA4 antibody, BFNC antibody, EBN antibody, EBN1 antibody, NACHR antibody, NACRA4 antibody, NARAC antibody, Acra-4 antibody, Acra4 antibody, ENFL1 antibody, neuronal acetylcholine receptor subunit alpha-4 antibody, neuronal acetylcholine receptor subunit alpha-4-like antibody, cholinergic receptor nicotinic alpha 4 subunit antibody, cholinergic receptor, nicotinic, alpha 4b antibody, cholinergic receptor, nicotinic, alpha polypeptide 4 antibody, CpipJ_CPIJ002434 antibody, LOC100368057 antibody, CHRNA4 antibody, chrna4b antibody, Chrna4 antibody
- 背景
- The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. After binding acetylcholine, the nAChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in nACHR4 are the cause of autosomal dominant nocturnal frontal lobe epilepsy type 1 (ENFL1) also symbolized ADNFLE. ENFL1 is a disease characterized by clusters of motor seizures during sleep. Polymorphisms in this gene that provide protection against nicotine addiction have been described.Synonyms: CHRNA4, NACRA4, Nicotinic acetylcholine receptor subunit alpha 4
- 分子量
- 70.0 kDa (Human NP_000735.1) and 70.2 kDa (Rat NP_077330.1)
- 基因ID
- 25590
- NCBI登录号
- NP_077330
- UniProt
- P09483
- 途径
- Synaptic Membrane
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