CHRNA4 产品
(Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
Categories
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
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Featured CHRNA4 Categories
CHRNA4 抗体
High quality antibodies with extensive validation data.
CHRNA4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CHRNA4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CHRNA4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (5)
Cat. No.
ABIN7444463
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS, Neut
Validations
- (4)
Cat. No.
ABIN5611309
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (3)
Cat. No.
ABIN736746
Quantity
100 μL
Datasheet
Datasheet
Recommended CHRNA4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN456521
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1144815
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1144816
Quantity
96 tests
Datasheet
Datasheet
Recommended CHRNA4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349402
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3087989
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3087990
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CHRNA4 Products
: "Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors." in: BMC cancer, Vol. 15, pp. 152, (2015) (PubMed).: "Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." in: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).
: "Enhanced expression of hypersensitive alpha4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 7, pp. 935-46, (2006) (PubMed).
: "How mutations in the nAChRs can cause ADNFLE epilepsy." in: Epilepsia, Vol. 43 Suppl 5, pp. 112-22, (2002) (PubMed).
Synonyms and alternative names related to CHRNA4
neuronal acetylcholine receptor subunit alpha-4 (CpipJ_CPIJ002434), neuronal acetylcholine receptor subunit alpha-4-like (LOC100368057), cholinergic receptor nicotinic alpha 4 subunit (CHRNA4), cholinergic receptor, nicotinic, alpha 4b (chrna4b), cholinergic receptor nicotinic alpha 4 subunit (Chrna4), cholinergic receptor, nicotinic, alpha polypeptide 4 (Chrna4), Acra-4, Acra4, BFNC, EBN, EBN1, ENFL1, NACHR, NACHRA4, NACRA4, NARACProtein level used designations for CHRNA4
- neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor subunit alpha-4-like
- cholinergic receptor, nicotinic, alpha 4
- neuronal acetylcholine receptor subunit alpha-4-like
- neuronal nicotinic acetylcholine receptor alpha 4 subunit
- alpha-4 subunit, nicotinic acetylcholine receptor
- cholinergic receptor, nicotinic, alpha polypeptide 4
- neuronal nicotinic acetylcholine receptor alpha-4 subunit
- Neuronal nicotinic acetylcholine receptor alpha 4 subunit
- cholinergic receptor, nicotinic, alpha 4 subunit
- neuronal acetylcholine receptor alpha-4 subunit
- a4 nicotinic receptor
- acetylcholine receptor alpha 4 neural
- acetylcholine receptor, neuronal, nicotinic, alpha-4 subunit
- alpha4 nAChR
- alpha4-nAChR
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- Chromatin Target of PRMT1
- Chromogranin A
- Chromosome 1 Open Reading Frame 190
- Chromosome 1 Open Reading Frame 27
- Chromosome 1 Open Reading Frame 61
- Chromosome 1 Open Reading Frame 84
- Chromosome 10 Open Reading Frame 116
- Chromosome 11open Reading Frame 9
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