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FBXO32 抗体 (Internal Region, Isoform 1)

FBXO32 适用: 人, 大鼠, 小鼠, Cow, Pig WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375094
发货至: 中国
  • 抗原 See all FBXO32 抗体
    FBXO32 (F-Box Protein 32 (FBXO32))
    抗原表位
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region, Isoform 1
    适用
    • 48
    • 38
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠, Cow, Pig
    宿主
    • 45
    • 6
    • 1
    山羊
    克隆类型
    • 40
    • 12
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO32 antibody is un-conjugated
    应用范围
    • 37
    • 14
    • 14
    • 13
    • 12
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody is expected to recognize reported isoform 1 (FBXO32).
    交叉反应 (详细)
    Species reactivity (expected):Rat, Bovine and Porcine.
    Species reactivity (tested):Human, Mouse
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence: C-NSKTKTQYFHQEK from the internal region of F-box only protein 32 isoform 1 / FBXO32
    Top Product
    Discover our top product FBXO32 Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit: 1/32000. Western Blot: 0.1-0.3 μg/mL. Approx.40 kDa band observed in Human and Mouse SkeletalMuscle lysates (calculated MW of 41.0 kDa according to Human NP_478136.1 and of41.0 kDa according to Mouse NP_080622.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FBXO32 (F-Box Protein 32 (FBXO32))
    别名
    FBXO32 (FBXO32 产品)
    别名
    MGC56479 antibody, zgc:56479 antibody, Fbx32 antibody, MAFbx antibody, 4833442G10Rik antibody, AI430017 antibody, ATROGIN1 antibody, Gm20361 antibody, Atrogin1 antibody, F-box protein 32 antibody, fbxo32 antibody, FBXO32 antibody, Fbxo32 antibody
    背景
    Fbx32 is an E3 ubiquitin ligase that initiates ATP dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. It is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. It is also thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. Fbx32 interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD.Synonyms: Atrogin-1, F-box only protein 32, FBXO32, MAFbx, Muscle atrophy F-box protein
    基因ID
    114907, 9606
    UniProt
    Q969P5
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