KCNJ11 抗体 (Internal Region, N-Term)
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- 抗原 See all KCNJ11 抗体
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
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抗原表位
- Internal Region, N-Term
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This KCNJ11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 序列
- C-AEDPAKPRYR ARQ
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- 免疫原
- Peptide from the internal region (near the N Terminus) of the protein sequence according to NP_000516.3 Genename: KCNJ11
- Top Product
- Discover our top product KCNJ11 Primary Antibody
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 172-390) antibody
KCNJ11 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (pThr224) antibodyKCNJ11 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) antibodyKCNJ11 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 301-390) antibodyKCNJ11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Internal Region) antibodyVerified KCNJ11 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Center) antibodyKCNJ11 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 190-239) antibodyKCNJ11 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 372-385), (C-Term), (Intracellular) antibodyKCNJ11 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 豚鼠 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Ser688) antibodyKCNJ11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 171-390) antibodyKCNJ11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: Limit Dilution: 1/32000. Western blot: 0.1-0.3 μg/mL. Approx 45-48 kDa band observed in Human Skeletal Musclelysates (calculated MW of 43.8 kDa according to NP_000516.3). Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Pancreas shows variablestaining across the islet of Langerhans.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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- 抗原
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
- 别名
- KCNJ11 (KCNJ11 产品)
- 别名
- kir6.2 antibody, Kir6.2 antibody, mBIR antibody, BIR antibody, HHF2 antibody, IKATP antibody, KIR6.2 antibody, PHHI antibody, TNDM3 antibody, potassium voltage-gated channel subfamily J member 11 antibody, potassium inwardly-rectifying channel, subfamily J, member 11 antibody, potassium inwardly rectifying channel, subfamily J, member 11 antibody, KCNJ11 antibody, kcnj11 antibody, Kcnj11 antibody
- 背景
- ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus.Synonyms: ATP-sensitive inward rectifier potassium channel 11, IKATP, Inward rectifier K+ channel Kir6.2, KCNJ11, Potassium channel, inwardly rectifying subfamily J member 11
- 基因ID
- 9606
- UniProt
- Q14654
- 途径
- Negative Regulation of Hormone Secretion
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