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KCNJ11 抗体 (AA 171-390)

KCNJ11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6142721
发货至: 中国
  • 抗原 See all KCNJ11 抗体
    KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
    抗原表位
    • 25
    • 17
    • 14
    • 13
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-390
    适用
    • 88
    • 53
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 85
    • 1
    • 1
    • 1
    克隆类型
    • 88
    多克隆
    标记
    • 29
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This KCNJ11 antibody is un-conjugated
    应用范围
    • 76
    • 44
    • 28
    • 26
    • 26
    • 14
    • 11
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    TAQAHRRAET LIFSKHAVIA LRHGRLCFML RVGDLRKSMI ISATIHMQVV RKTTSPEGEV VPLHQVDIPM ENGVGGNSIF LVAPLIIYHV IDANSPLYDL APSDLHHHQD LEIIVILEGV VETTGITTQA RTSYLADEIL WGQRFVPIVA EEDGRYSVDY SKFGNTVKVP TPLCTARQLD EDHSLLEALT LASARGPLRK RSVPMAKAKP KFSISPDSLS
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 171-390 of human KCNJ11 (NP_000516.3).
    亚型
    IgG
    Top Product
    Discover our top product KCNJ11 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
    别名
    KCNJ11 (KCNJ11 产品)
    别名
    kir6.2 antibody, Kir6.2 antibody, mBIR antibody, BIR antibody, HHF2 antibody, IKATP antibody, KIR6.2 antibody, PHHI antibody, TNDM3 antibody, potassium voltage-gated channel subfamily J member 11 antibody, potassium inwardly-rectifying channel, subfamily J, member 11 antibody, potassium inwardly rectifying channel, subfamily J, member 11 antibody, KCNJ11 antibody, kcnj11 antibody, Kcnj11 antibody
    背景
    Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.,KCNJ11,BIR,HHF2,IKATP,KIR6.2,MODY13,PHHI,TNDM3,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Cardiovascular,Hypoxia,Heart,Cardiac arrhythmias,KCNJ11
    分子量
    33 kDa/43 kDa
    基因ID
    3767
    UniProt
    Q14654
    途径
    Negative Regulation of Hormone Secretion
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