DIO2 抗体 (Internal Region)
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- 抗原 See all DIO2 抗体
- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠, Pig
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This DIO2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is expected to recognise both reported isoform a and isoform b of DIO2.
- 交叉反应 （详细）
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Species reactivity (expected):Human, Rat and Porcine.
Species reactivity (tested):Mouse. - 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography
- 免疫原
- Peptide with sequence EVKKHQNQEDRC, from the internal region of the protein sequence
- Top Product
- Discover our top product DIO2 Primary Antibody
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anti-Deiodinase, Iodothyronine, Type II (DIO2) (Internal Region) antibody
Verified DIO2 适用: 人, 小鼠 ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 165-191) antibodyDIO2 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22907 unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 74-222) antibodyDIO2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 165-191) antibodyDIO2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 101-200) antibodyDIO2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) antibodyDIO2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 30-259) antibodyDIO2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) antibodyDIO2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 171-200), (Middle Region) antibodyDIO2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: Detection limit: 1/128000. Western Blot: Preliminary experiments gave an approx 65-70 kDa band in Human Heart andThyroid lysates after 0.05 μg/mL DIO2 antibody staining. Immunohistochemistry: 2-3 μg/mL. Cryo-sectioned Mouse Brain (Hippocampus) showsstaining in the granular layer of the dentate gyrus.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris Saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
- 别名
- DIO2 (DIO2 产品)
- 别名
- 5DII antibody, D2 antibody, DIOII antibody, SelY antibody, TXDI2 antibody, AI324267 antibody, Deio2 antibody, cb684 antibody, DIO2 antibody, dio2-A antibody, 5dii antibody, sely antibody, txdi2 antibody, iodothyronine deiodinase 2 antibody, deiodinase, iodothyronine, type II antibody, deiodinase, iodothyronine, type 2 L homeolog antibody, deiodinase, iodothyronine, type 2 antibody, type II iodothyronine deiodinase antibody, DIO2 antibody, Dio2 antibody, dio2 antibody, dio2.L antibody, LOC100861220 antibody
- 背景
- DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). It is essential for providing the brain with appropriate levels of T3 during the critical period of development. DIO2 is expressed in heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. There are two named isoforms.Synonyms: DIOII, ITDI2, TXDI2, Type II iodothyronine deiodinase, Type-II 5'-deiodinase
- 基因ID
- 1734
- NCBI登录号
- NP_000784
- UniProt
- Q92813
- 途径
- Hormone Transport, Hormone Activity
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