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DIO2 抗体

DIO2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7002875
发货至: 中国
  • 抗原 See all DIO2 抗体
    DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
    适用
    人, 小鼠, 大鼠
    宿主
    • 42
    • 1
    • 1
    克隆类型
    • 43
    • 1
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DIO2 antibody is un-conjugated
    应用范围
    • 31
    • 17
    • 13
    • 13
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human DIO2
    亚型
    IgG
    Top Product
    Discover our top product DIO2 Primary Antibody
  • 应用备注
    WB 1:200-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.7 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
    别名
    DIO2 (DIO2 产品)
    别名
    5DII antibody, D2 antibody, DIOII antibody, SelY antibody, TXDI2 antibody, AI324267 antibody, Deio2 antibody, cb684 antibody, DIO2 antibody, dio2-A antibody, 5dii antibody, sely antibody, txdi2 antibody, iodothyronine deiodinase 2 antibody, deiodinase, iodothyronine, type II antibody, deiodinase, iodothyronine, type 2 L homeolog antibody, deiodinase, iodothyronine, type 2 antibody, type II iodothyronine deiodinase antibody, DIO2 antibody, Dio2 antibody, dio2 antibody, dio2.L antibody, LOC100861220 antibody
    背景
    The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
    分子量
    31 kDa
    NCBI登录号
    NP_000784
    UniProt
    Q92813
    途径
    Hormone Transport, Hormone Activity
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