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AKR1C3 抗体 (C-Term)

AKR1C3 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374516
发货至: 中国
  • 抗原 See all AKR1C3 抗体
    AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 54
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 64
    • 3
    • 1
    • 1
    山羊
    克隆类型
    • 66
    • 2
    多克隆
    标记
    • 28
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C3 antibody is un-conjugated
    应用范围
    • 61
    • 34
    • 18
    • 14
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    特异性
    This antibody reacts to AKR1C3.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence CFASHPNYPYSDEY, from the C Terminus of the protein sequence
    Top Product
    Discover our top product AKR1C3 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32000. Western Blot: 0.01 - 0.1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
    Abstract
    AKR1C3 产品
    别名
    AKR1C3 antibody, PGFS antibody, MGC134333 antibody, DD3 antibody, DDX antibody, HA1753 antibody, HAKRB antibody, HAKRe antibody, HSD17B5 antibody, hluPGFS antibody, Akr1c18 antibody, aldo-keto reductase family 1, member C3 L homeolog antibody, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) antibody, aldo-keto reductase family 1 member C2 antibody, aldo-keto reductase family 1 member C3 antibody, aldo-keto reductase family 1, member C3 antibody, akr1c3.L antibody, AKR1C3 antibody, LOC722496 antibody, Akr1c3 antibody
    背景
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20 alpha hydroxy progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation.Synonyms: 17-beta-hydroxysteroid dehydrogenase type 5, 2-dihydrobenzene-1, 2-diol dehydrogenase, 3-alpha-HSD type II, 3-alpha-HSD type II, 3-alpha-hydroxysteroid dehydrogenase type 2, Aldo-keto reductase family 1 member C3, Chlordecone reductase homolog HAKRb, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydrogenase type I, HA1753, HSD17B5, KIAA0119, PGFS, Prostaglandin F synthase, Testosterone 17-beta-dehydrogenase 5, Trans-1, brain
    基因ID
    8644, 9606
    UniProt
    P42330
    途径
    Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
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