AKR1C3 抗体 (C-Term)
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- 抗原 See all AKR1C3 抗体
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKR1C3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 交叉反应
- 人, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to AKR1C3 (aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II))
AKR1C3 antibody [C2C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AKR1C3. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product AKR1C3 Primary Antibody
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- 应用备注
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: rat liver , HepG2 , HeLa
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
- 别名
- aldo-keto reductase family 1 member C3 (AKR1C3 产品)
- 别名
- AKR1C3 antibody, PGFS antibody, MGC134333 antibody, DD3 antibody, DDX antibody, HA1753 antibody, HAKRB antibody, HAKRe antibody, HSD17B5 antibody, hluPGFS antibody, Akr1c18 antibody, aldo-keto reductase family 1, member C3 L homeolog antibody, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) antibody, aldo-keto reductase family 1 member C2 antibody, aldo-keto reductase family 1 member C3 antibody, aldo-keto reductase family 1, member C3 antibody, akr1c3.L antibody, AKR1C3 antibody, LOC722496 antibody, Akr1c3 antibody
- 背景
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Cellular Localization: Cytoplasm - 分子量
- 37 kDa
- 基因ID
- 8644
- UniProt
- P42330
- 途径
- Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
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