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PPARD 抗体 (C-Term, Isoform 1)

PPARD 适用: 人, 小鼠, 大鼠, Cow, Pig WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374465
发货至: 中国
  • 抗原 See all PPARD 抗体
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    抗原表位
    • 16
    • 13
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, Isoform 1
    适用
    • 83
    • 30
    • 20
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, Pig
    宿主
    • 80
    • 10
    • 1
    山羊
    克隆类型
    • 82
    • 9
    多克隆
    标记
    • 46
    • 11
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPARD antibody is un-conjugated
    应用范围
    • 81
    • 41
    • 28
    • 16
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    CHPLLQEIYK DMY
    特异性
    This antibody is expected to recognize isoform 1 (NP_006229) of PPAR delta, but not isoform 2, a shorter protein (NP_803184) with a different C-terminus.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Porcine, Bovine.
    Species reactivity (tested):Human, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence from the C Terminus of the protein sequence according to NP_006229.1. Genename: PPARD
    Top Product
    Discover our top product PPARD Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western blot: 0.3 - 1 μg/mL
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    别名
    PPAR-delta (PPARD 产品)
    别名
    FAAR antibody, NR1C2 antibody, NUC1 antibody, NUCI antibody, NUCII antibody, PPARB antibody, NUC-1 antibody, Nr1c2 antibody, PPAR-beta antibody, PPAR-delta antibody, PPAR[b] antibody, PPARdelta antibody, Pparb antibody, Pparb/d antibody, PPARBETA antibody, ppard antibody, pparb antibody, PPARD antibody, PPAR-D/B antibody, peroxisome proliferator activated receptor delta antibody, peroxisome proliferator activator receptor delta antibody, peroxisome proliferator activated receptor delta S homeolog antibody, peroxisome proliferator-activated receptor delta antibody, PPARD antibody, Ppard antibody, ppard.S antibody, ppard antibody
    背景
    PPARD is a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta. PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.Synonyms: NR1C2, NUCI, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2, PPAR-beta, PPARB, PPARD, Peroxisome proliferator-activated receptor delta
    基因ID
    5467
    NCBI登录号
    NP_001165289
    UniProt
    Q03181
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
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