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CPEB1 抗体 (C-Term)

CPEB1 适用: 人, Macaque WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374439
发货至: 中国
  • 抗原 See all CPEB1 抗体
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    抗原表位
    • 15
    • 10
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 49
    • 4
    • 4
    人, Macaque
    宿主
    • 46
    • 2
    • 1
    山羊
    克隆类型
    • 49
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPEB1 antibody is un-conjugated
    应用范围
    • 44
    • 25
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    C-PLMRNQKNRD SS
    特异性
    This antibody recognizes CPEB1.
    交叉反应 (详细)
    Species reactivity (expected):Macaque.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide from the C Terminus of the protein sequence according to NP_085097.
    Top Product
    Discover our top product CPEB1 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/128000. Western Blot: 0.5-2.0 μg/mL. Approx 65-70 kDa band observed in Human Brain lysates(predicted MW of 60 kDa according to NP_085097). Please note this band was always accompanied by a slightly stonger band at approx 40 kDaand further both bands could be blocked by incubation with the immunising peptide.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    别名
    CPEB1 (CPEB1 产品)
    别名
    CEBP antibody, CPE-BP1 antibody, CPEB antibody, AU024112 antibody, Cpeb antibody, mCPEB antibody, CPEB1 antibody, cpeb1 antibody, ZOR-1 antibody, cepb1b antibody, fd15c06 antibody, wu:fd15c06 antibody, zorba antibody, cytoplasmic polyadenylation element binding protein 1 antibody, hypothetical protein antibody, cytoplasmic polyadenylation element binding protein 1 L homeolog antibody, cytoplasmic polyadenylation element binding protein 1b antibody, cytoplasmic polyadenylation element binding protein 1 S homeolog antibody, CPEB1 antibody, Cpeb1 antibody, cpeb1 antibody, LOAG_17395 antibody, cpeb1.L antibody, cpeb1b antibody, cpeb1.S antibody
    背景
    The regulated translation of messenger RNA is essential for cell cycle progression, establishment of the body plan during early development, and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, which is one mechanism of controlling translation, is driven by CPEB1 (Cytoplasmic Polyadenylation Element Binding protein), a highly conserved, sequence specific RNA binding protein that binds to the cytoplasmic polyadenylation element (CPE) and modulates translational repression and mRNA localisation. CPEB1 can assemble bothe translational activation and repression complexes via its binding to the CPE. In both vertebrates and invertebrates, the expression of several maternal mRNAs is regulated by cytoplasmic polyadenylation. In Xenopus oocytes, where most of the biochemical details of this process have been examined, polyadenylation is controlled by CPEB1.Synonyms: CPE-BP1, CPE-binding protein 1, Cytoplasmic polyadenylation element-binding protein 1, h-CEBP, hCPEB-1
    基因ID
    64506
    NCBI登录号
    NP_001073001
    UniProt
    Q9BZB8
    途径
    Synaptic Membrane
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