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SIRT4 抗体 (C-Term)

Name: SIRT4 抗体 (C-Term)
SKU: ABIN374409
Availability: OutOfStock

SIRT4 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated

Image no. 2 for anti-Sirtuin 4 (SIRT4) (C-Term) antibody (ABIN374409) (SIRT4 抗体 (C-Term))

Image no. 1 for anti-Sirtuin 4 (SIRT4) (C-Term) antibody (ABIN374409) (SIRT4 抗体 (C-Term))

Image no. 3 for anti-Sirtuin 4 (SIRT4) (C-Term) antibody (ABIN374409) (SIRT4 抗体 (C-Term))

3 images

(2 references)

产品编号 ABIN374409

发货至: 中国

Datasheet as PDF

抗原 See all SIRT4 抗体

SIRT4 (Sirtuin 4 (SIRT4))
抗原表位
12

11

8

6

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
C-Term
适用
51

35

25

5

4

4

3

3

3

2

1

1

1

1

1

1
人, 小鼠, 大鼠, Cow, 犬, Pig
宿主
51

8

2

1
山羊
Compatible Secondaries
克隆类型
56

6
多克隆
标记
31

10

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
This SIRT4 antibody is un-conjugated
应用范围
57

27

15

4

4

4

4

2

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

序列

SRCGELLPLI DPC

特异性

This antibody detects SIRT4 at C-term.

交叉反应（详细）

Species reactivity (expected):Mouse, Canine (Dog), Pig, Cow.
Species reactivity (tested):Human, Rat.

纯化方法

Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

免疫原

Peptide from C-Terminus of the protein sequence according to NP_036372.1 Genename: SIRT4

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anti-Sirtuin 4 (SIRT4) (AA 51-150) antibody
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anti-Sirtuin 4 (SIRT4) (AA 60-255) antibody
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anti-Sirtuin 4 (SIRT4) (C-Term) antibody
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anti-Sirtuin 4 (SIRT4) (AA 215-314) antibody
SIRT4 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G6D2 unconjugated

anti-Sirtuin 4 (SIRT4) (Middle Region) antibody
SIRT4 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 4 (SIRT4) (AA 29-260) antibody
SIRT4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 4 (SIRT4) (AA 26-333) antibody
SIRT4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 4 (SIRT4) (AA 215-314) antibody
SIRT4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C8 unconjugated

anti-Sirtuin 4 (SIRT4) (AA 216-265) antibody
SIRT4 适用: 人, 犬, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Peptide ELISA: 1/32000. Western blot: Approx.38 kDa band observed in Human Kidney and U937 lysates(calculated MW of 35.8 kDa according to NP_036372.1). In transfected HEK293 transientlyexpressing SIRT4 a band of approx.38 kDa is observed. This band is not observed in thenon-transfected HEK293. Recommended Concentration: 1-3 μg/mL. Immunohistochemistry on Paraffin Sections: Skeletal Muscle shows spotty staining ofstriated fibres in longitudinal section. Recommended Concentration: 2-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Ott, Plitzko, Krischkowski, Reichmann, Bittner, Mendel, Kunze, Clement, Havemeyer: "Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC)." in: Chemical research in toxicology, Vol. 27, Issue 10, pp. 1687-95, (2015) (PubMed).

Ahuja, Schwer, Carobbio, Waltregny, North, Castronovo, Maechler, Verdin: "Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase." in: The Journal of biological chemistry, Vol. 282, Issue 46, pp. 33583-92, (2007) (PubMed).
抗原

SIRT4 (Sirtuin 4 (SIRT4))

别名

SIRT4 (SIRT4 产品)

别名

SIRT4 antibody, im:7139453 antibody, SIR2L4 antibody, 4930596O17Rik antibody, sirtuin 4 antibody, SIRT4 antibody, sirt4 antibody, Sirt4 antibody

背景

SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.Synonyms: NAD-Dependent ADP-Ribosyltransferase Sirtuin-4, SIR2-like 4, SIR2L4, SIRT-4, sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae), sirtuin 4, sirtuin type 4, sirtuin-4

基因ID

23409

NCBI登录号

NP_036372

UniProt

Q9Y6E7

途径

Negative Regulation of Hormone Secretion