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SORL1 抗体 (C-Term)

SORL1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374076
发货至: 中国
  • 抗原 See all SORL1 抗体
    SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
    抗原表位
    • 15
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, Cow, 犬
    宿主
    • 35
    • 6
    • 2
    • 1
    山羊
    克隆类型
    • 39
    • 5
    多克隆
    标记
    • 20
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SORL1 antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    序列
    C-TGFSDDVPMV IA
    特异性
    This antibody detects Sortilin-Related Receptor at C-term.
    交叉反应 (详细)
    Species reactivity (expected):Human, Rat, Canine (Dog), Bovine.
    Species reactivity (tested):Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from the C Terminus of the protein according to NP_003096.1. Genename: SORL1
    Top Product
    Discover our top product SORL1 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx 250 kDa band observed in Mouse and Rat Brain lysates(calculated MW of 240 kDa according to Human NP_003096.1, and 240 kDa accordnig toMouse NP_035566.2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
    别名
    Sortilin-Related Receptor (SORL1) (SORL1 产品)
    别名
    SORL1 antibody, C11orf32 antibody, LR11 antibody, LRP9 antibody, SORLA antibody, SorLA-1 antibody, gp250 antibody, SorLA antibody, 2900010L19Rik antibody, AI596264 antibody, AW261561 antibody, mSorLA antibody, Lr11 antibody, RGD619914 antibody, sortilin related receptor 1 antibody, sortilin-related receptor antibody, sortilin-related receptor, L(DLR class) A repeats containing antibody, sortilin-related receptor, L(DLR class) A repeats-containing antibody, sortilin-related receptor, LDLR class A repeats-containing antibody, sorl1 antibody, LOC582560 antibody, SORL1 antibody, Sorl1 antibody
    背景
    Sortilin-related receptor (SORL1) is likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. Expressed mainly in brain, where it is most abundant in the cerebellum, cerebral cortex and the occipital pole, low expression in the putamen and the thalamus. According to PubMed:9157966, found in spinal cord, testis, liver, kidney and pancreas with detectable levels in placenta, lung and heart. According to PubMed:8940146, expressed in the prostate, ovary, thyroid and spleen, but not found in kidney, liver, lung, skeletal muscle, bone marrow and adrenals.Synonyms: LR11, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, SorLA, SorLA-1, Sorting protein-related receptor containing LDLR class A repeats
    基因ID
    6653
    NCBI登录号
    NP_003096
    UniProt
    Q92673
    途径
    Smooth Muscle Cell Migration
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