电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KCNC1 抗体 (pSer503)

KCNC1 适用: 小鼠, 大鼠 WB, IF, IHC (fro), DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372706
发货至: 中国
  • 抗原 See all KCNC1 抗体
    KCNC1 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1))
    抗原表位
    • 16
    • 15
    • 9
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer503
    适用
    • 61
    • 15
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 63
    • 1
    克隆类型
    • 63
    • 1
    多克隆
    标记
    • 17
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This KCNC1 antibody is un-conjugated
    应用范围
    • 52
    • 26
    • 26
    • 25
    • 15
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)
    特异性
    This antibody recognizes the ~100k KCNC1 (Kv3.1) protein phosphorylated at Ser503 in Rat brain extracts.
    交叉反应 (详细)
    Species reactivity (tested):Rat and Mouse.
    纯化方法
    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser503 of KCNC1 conjugated to keyhole limpet hemocyanin (KLH).
    亚型
    IgG
    Top Product
    Discover our top product KCNC1 Primary Antibody
  • 应用备注
    Dot Blot: 1/1000. Western blot: 1/1000. Immunohistochemistry on Frozen Sections: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • Ahmed, Spikings, Zhou, Thompsett, Zhang: "Pre-hybridisation: an efficient way of suppressing endogenous biotin-binding activity inherent to biotin-streptavidin detection system." in: Journal of immunological methods, Vol. 406, pp. 143-7, (2014) (PubMed).

    Gupta, Palmer, Spence, Hudson, Stephens: "Kinesin-1 (uKHC/KIF5B) is required for bidirectional motility of ER exit sites and efficient ER-to-Golgi transport." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 11, pp. 1850-66, (2008) (PubMed).

    Chernova, Steinert, Guerin, Nicotera, Forsythe, Smith: "Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 32, pp. 8475-85, (2007) (PubMed).

  • 抗原
    KCNC1 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1))
    别名
    KCNC1 (KCNC1 产品)
    别名
    kv3.1 antibody, C230009H10Rik antibody, KShIIIB antibody, KV4 antibody, Kcr2-1 antibody, Kv3.1 antibody, NGK2 antibody, Shaw antibody, Kv4 antibody, NGK2-KV4 antibody, KV3.1 antibody, KCNC2 antibody, zgc:194940 antibody, zgc:194950 antibody, potassium voltage-gated channel subfamily C member 1 antibody, potassium voltage-gated channel, Shaw-related subfamily, member 1 antibody, potassium voltage gated channel, Shaw-related subfamily, member 1 antibody, potassium voltage-gated channel, Shaw-related subfamily, member 1a antibody, KCNC1 antibody, kcnc1 antibody, Kcnc1 antibody, kcnc1a antibody
    背景
    Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995, Pongs, 1999, Blaine and Ribera, 1998, Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).Synonyms: Kv4, NGK2, Potassium voltage-gated channel subfamily C member 1, Voltage-gated potassium channel subunit Kv3.1
    基因ID
    25327
    NCBI登录号
    NP_036988
    UniProt
    P25122
You are here:
客服