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ATG7 抗体 (N-Term)

ATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372502
发货至: 中国
  • 抗原 See all ATG7 抗体
    ATG7 (ATG7 Autophagy Related 7 (ATG7))
    抗原表位
    • 16
    • 16
    • 15
    • 9
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 117
    • 40
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 105
    • 13
    • 2
    克隆类型
    • 101
    • 19
    多克隆
    标记
    • 59
    • 9
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG7 antibody is un-conjugated
    应用范围
    • 99
    • 59
    • 46
    • 24
    • 17
    • 14
    • 14
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognizes Ubiquitin Activating Enzyme E1-like Protein (GSA7/ATG7).
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide corresponding to 17 amino acids peptide from near the amino terminus of human APG7.
    亚型
    IgG
    Top Product
    Discover our top product ATG7 Primary Antibody
  • 应用备注
    Western blot: 1-2 μg/mL. Immunocytochemistry. Immunohistochemistry on Paraffin sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    ATG7 (ATG7 Autophagy Related 7 (ATG7))
    别名
    APG7L / ATG7 (ATG7 产品)
    别名
    APG7-LIKE antibody, APG7L antibody, GSA7 antibody, D8 antibody, UBA1B antibody, UBE1L antibody, UBE2 antibody, Ube1l antibody, 1300004C08Rik antibody, AO090001000744 antibody, atg7 antibody, 1810013K23Rik antibody, Agp7 antibody, Apg7l antibody, Atg7l antibody, ATAPG7 antibody, ATATG7 antibody, ATG7 antibody, AUTOPHAGY 7 antibody, AUTOPHAGY-RELATED 7 antibody, K15I22.10 antibody, K15I22_10 antibody, autophagy related 7 antibody, ubiquitin like modifier activating enzyme 7 antibody, ubiquitin-like modifier activating enzyme 7 antibody, autophagy-related protein 7 antibody, Autophagy-related protein 7 antibody, Apg7p antibody, ThiF family protein antibody, ubiquitin-like conjugating enzyme Atg7 antibody, ATG7 antibody, UBA7 antibody, Uba7 antibody, ANI_1_3368024 antibody, AOR_1_1338164 antibody, PTRG_02236 antibody, PAAG_00287 antibody, PITG_12537 antibody, atg7 antibody, Atg7 antibody, APG7 antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by Target of rapamycin (TOR) via phosphorylation of autophagy protein APG1. APG7 is a member of the autophagy family of proteins and was identified in yeast as a ubiquitin-E1-like enzyme, this function is conserved in the mammalian homolog. In mammalian cells, APG7 is essential for autophagy conjugation systems, autophagosome formation, starvation-induced bulk degradation of proteins and organelles. It has been suggested that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death.Synonyms: APG7-like, Autophagy-related protein 7, Ubiquitin-activating enzyme E1-like protein
    基因ID
    10533
    NCBI登录号
    NP_001129503
    UniProt
    O95352
    途径
    Response to Water Deprivation, Autophagy
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