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BAFF 抗体 (C-Term)

TNFSF13B 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372454
发货至: 中国
  • 抗原 See all BAFF (TNFSF13B) 抗体
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    抗原表位
    • 16
    • 9
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    • 2
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    • 2
    • 1
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    • 1
    • 1
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    • 1
    • 1
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    AA 254-269, C-Term
    适用
    • 113
    • 31
    • 29
    • 2
    • 2
    • 2
    人, 小鼠
    宿主
    • 77
    • 34
    • 17
    • 9
    克隆类型
    • 87
    • 50
    多克隆
    标记
    • 69
    • 19
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    • 1
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    This BAFF antibody is un-conjugated
    应用范围
    • 81
    • 58
    • 48
    • 36
    • 15
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    • 13
    • 11
    • 10
    • 8
    • 8
    • 5
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognizes CD257/BAFF.
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Protein G Chromatography.
    免疫原
    Synthetic peptide corresponding to amino acids 254-269 (C-terminal) of Human BAFF.
    亚型
    IgG
    Top Product
    Discover our top product TNFSF13B Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western blot: 0.5-2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.2 mLPBS containing 0.05 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    别名
    CD257 / BAFF (TNFSF13B 产品)
    别名
    BAFF antibody, BLYS antibody, CD257 antibody, DTL antibody, TALL-1 antibody, TALL1 antibody, THANK antibody, TNFSF20 antibody, ZTNF4 antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, TNFSF13B antibody, RGD1561519 antibody, RGD1560810 antibody, BLyS antibody, D8Ertd387e antibody, zTNF4 antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, zgc:172115 antibody, TNF superfamily member 13b antibody, TNF receptor superfamily member 13C antibody, tumor necrosis factor (ligand) superfamily, member 13b antibody, tumor necrosis factor receptor superfamily, member 13c antibody, tumor necrosis factor superfamily member 13b antibody, TNFSF13B antibody, TNFRSF13C antibody, Tnfsf13b antibody, Tnfrsf13c antibody, tnfsf13b antibody
    背景
    Simultaneously four different laboratories identified a new member of the tumor necrosis factor (TNF) family. This has been named as TALL-1, THANK (TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase, BAFF (for B cell activating factor belonging to the TNF family) and Blys (B lymphocyte stimulator). Membrane-bound BAFF is processed and secreted through the action of a protease whose specificity matches that of the furin family of proprotein convertases. Secreted BLyS/BAFF/THANK acts as a potent B cell growth factor. This protein is expressed abundantly in peripheral blood lymphocytes, specifically in monocytes and macrophages. Its regulation is upregulated by interferon gamma. Overexpression of BLyS/BAFF in transgenic mice lead to increased numbers of mature B and effector T cells. These mice also develop autoimmune like symptoms, such as, high levels of rheumatoid factors, anti-DNA autoantibodies, etc. Two receptors for BLyS/BAFF have been identified and termed as BCMA and TACI.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4
    基因ID
    10673
    NCBI登录号
    NP_001139117
    UniProt
    Q9Y275
    途径
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
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