TNFRSF11A 抗体 (AA 603-613)
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- 抗原 See all TNFRSF11A 抗体
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
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抗原表位
- AA 603-613
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF11A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody recognizes CD265/RANK.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - 纯化方法
- Protein G Chromatography.
- 免疫原
- KLH conjugated synthetic peptide corresponding to Amino acids residues 603-613 of Human RANK.
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF11A Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 330-615) antibody
TNFRSF11A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 359-542) antibodyTNFRSF11A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-214) antibodyTNFRSF11A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-130) antibodyTNFRSF11A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) antibodyTNFRSF11A 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1B5D10 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 51-150) antibodyTNFRSF11A 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 101-200) antibodyTNFRSF11A 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 330-615) antibodyTNFRSF11A 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D13 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 28-202) antibodyTNFRSF11A 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) antibodyTNFRSF11A 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
- 别名
- CD265 / RANK (TNFRSF11A 产品)
- 别名
- RANK antibody, RGD1563614 antibody, TNFRSF11A antibody, Ly109 antibody, ODFR antibody, OFE antibody, Rank antibody, TRANCE-R antibody, mRANK antibody, CD265 antibody, FEO antibody, LOH18CR1 antibody, OPTB7 antibody, OSTS antibody, PDB2 antibody, TRANCER antibody, TNF receptor superfamily member 11A antibody, TNF receptor superfamily member 11a antibody, tumor necrosis factor receptor superfamily, member 11a, NFKB activator antibody, Tnfrsf11a antibody, TNFRSF11A antibody
- 背景
- RANK is a member of the tumor necrosis factor receptor (TNFR) family. Human and murine RANK share 81 % amino acid identity in their extracellular domains. RANK is widely expressed, with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. RANK is also expressed in dendritic cells. RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of RANK. TRANCE (TNF-related activation-induced cytokines, also known as RANK ligand, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for RANK. The biological functions mediated by RANK include activation of NFkappaB and cjun N-terminal kinase, enhancement of T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis. The soluble form of RANK is able to block TRANCE induced biological activity. The binding of anti-RANK to cell surface RANK triggers signal transduction and induces RANK mediated bioactivity.Synonyms: ODFR, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A
- 分子量
- 66 kDa.
- 基因ID
- 8792
- NCBI登录号
- NP_003830
- UniProt
- Q9Y6Q6
- 途径
- NF-kappaB Signaling
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