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ARHGEF11 抗体 (N-Term)

ARHGEF11 适用: 人, 大鼠, 小鼠, 小鸡, 猴, Cow, 犬, 马, Chimpanzee WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372272
发货至: 中国
  • 抗原 See all ARHGEF11 抗体
    ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-50, N-Term
    适用
    • 46
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 小鸡, 猴, Cow, 犬, 马, Chimpanzee
    宿主
    • 44
    • 2
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 18
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF11 antibody is un-conjugated
    应用范围
    • 40
    • 26
    • 13
    • 13
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognizes Rho Guanine Exchange Factor (GEF) 11 (ARHGEF11).
    交叉反应 (详细)
    Species reactivity (expected):Bovine, Chimpanzee, Chicken, Dog (Canine), Horse, Monkey, Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide corresponding to a portion of the amino acids 1-50 of Human ARHGEF11.
    亚型
    IgG
    Top Product
    Discover our top product ARHGEF11 Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.1-0.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
    别名
    ARHGEF11 (ARHGEF11 产品)
    别名
    ARHGEF11 antibody, GTRAP48 antibody, PDZ-RHOGEF antibody, B930073M02 antibody, E130307F09 antibody, PDZ-RhoGEF antibody, Prg antibody, RhoGEF antibody, mKIAA0380 antibody, Gtrap48 antibody, Rho guanine nucleotide exchange factor (GEF) 11 antibody, Rho guanine nucleotide exchange factor 11 antibody, rho guanine nucleotide exchange factor 11 antibody, arhgef11 antibody, ARHGEF11 antibody, Arhgef11 antibody, LOC511220 antibody
    背景
    ARHGEF11 (Rho guanine nucleotide exchange factor 11) acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. It exhibits transforming ability, associates with and modulates the actin cytoskeleton, regulates neurite outgrowth, and mediates activation of Rho in response to stimulation by activated Galpha12/13. Rat ARHGEF11 interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. ARHGEF11 is also thought to be involved in a pathway known to play a role in both insulin secretion and action.Synonyms: GTRAP48, KIAA0380, PDZ-RhoGEF, Rho guanine nucleotide exchange factor 11, RhoGEF glutamate transport modulator GTRAP48
    基因ID
    9826
    NCBI登录号
    NP_055599
    UniProt
    O15085
    途径
    Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
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