IL2 Receptor beta 抗体
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- 抗原 See all IL2 Receptor beta (IL2RB) 抗体
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This IL2 Receptor beta antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- This antibody recognises beta chain (Mr. 90-100 kDa) of the IL-2 Receptor. It does not block IL-2 binding. (Ref.1)
- 产品特性
- Synonyms: Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL2 Receptor beta, P70-75
- 纯化方法
- Purified
- 免疫原
- Rat myeloma YB2/0 transfected with truncated mouse IL-2RB cDNA. (Ref. 1)
- 克隆位点
- 5H4
- 亚型
- IgG2a
- Top Product
- Discover our top product IL2RB Primary Antibody
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anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) antibody
IL2RB 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 1G11C6 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (Internal Region) antibodyIL2RB 适用: 小鼠, 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB 适用: 人 FACS, IP, Func 宿主: 小鼠 Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibody (APC)IL2RB 适用: 人 FACS 宿主: 小鼠 Monoclonal TU27 APC
anti-Interleukin 2 Receptor, beta (IL2RB) (Tyr364) antibodyIL2RB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (N-Term) antibodyIL2RB 适用: 小鼠, 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Flow Cytometry. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- 别名
- CD122 / IL2RB (IL2RB 产品)
- 别名
- IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
- 背景
- The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the alpha chain which binds IL-2 with low affinity, (ii) the beta chain that binds IL-2 with high affinity, and (ii) the common gamma chain (gc) that does not bind IL-2. (Ref.2) The high affinity receptor complex is an alpha/beta/gamma heterotrimer with a Kd of 1.3 x 10e-11 M. (Ref.2) In mouse spleen, CD122 is expresed on ~30 % of CD8+ cells and all NK cells, but < 1 % of B cells and CD4+ T lymphocytes. In the thymus, its expression is confined to CD4-CD8+ single positive and CD4-CD8- double negative cells. (Ref.4) Cytoplasmic regions of the IL-2R beta chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes. (Ref.1,4)Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
- 基因ID
- 16185
- UniProt
- P16297
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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