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IL2 Receptor beta 抗体 (AA 27-240)

IL2RB 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 1G11C6 unconjugated
产品编号 ABIN5611139
发货至: 中国
  • 抗原 See all IL2 Receptor beta (IL2RB) 抗体
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    抗原表位
    • 29
    • 16
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-240
    适用
    • 91
    • 77
    • 16
    • 5
    • 1
    宿主
    • 85
    • 25
    • 20
    小鼠
    克隆类型
    • 86
    • 43
    • 1
    单克隆
    标记
    • 61
    • 10
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This IL2 Receptor beta antibody is un-conjugated
    应用范围
    • 72
    • 54
    • 37
    • 26
    • 26
    • 16
    • 14
    • 10
    • 10
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CD122 (AA: extra 27-240) expressed in E. coli.
    克隆位点
    1G11C6
    亚型
    IgG2b
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    别名
    CD122 (IL2RB 产品)
    别名
    IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
    背景

    Description: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.

    Aliases: IL2RB, IL15RB, P70-75

    分子量
    61 kDa
    基因ID
    3560
    HGNC
    3560
    途径
    JAK/STAT Signaling, Growth Factor Binding
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