KLRG1 抗体 (Biotin)
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- 抗原 See all KLRG1 抗体
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
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适用
- 小鼠
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宿主
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仓鼠
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克隆类型
- 单克隆
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标记
- This KLRG1 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody reacts with Killer Cell Lectin-like Receptor G1 (KLRG1 formerly known as mouse MAFA or 2F1-Ag). It stains 30-60 % of NK1.1+CD3- splenocytes, and a small fraction of T cells in all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL). (Ref.1,5)
- 产品特性
- Synonyms: KLRG1, CLEC15A, MAFA, MAFAL, Mast cell function-associated antigen, MAFA-like receptor,ITIM-containing receptor MAFA-L, Killer cell lectin-like receptor subfamily G member 1,C-type lectin domain family 15 member A
- 免疫原
- Activated NK (A-LAK) cells from B6 (H-2b) mice. (Ref. 1)
- 克隆位点
- 2F1
- 亚型
- IgG
- Top Product
- Discover our top product KLRG1 Primary Antibody
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- 应用备注
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Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1,5)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
- 别名
- KLRG1 (KLRG1 产品)
- 别名
- KLRG1 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, 2F1 antibody, CLEC15A antibody, MAFA-2F1 antibody, MAFA-LIKE antibody, killer cell lectin like receptor G1 antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, KLRG1 antibody, Klrg1 antibody
- 背景
- Killer cell lectin-like receptor G1 (KLRG1, formerly known as mouse MAFA or 2F1 Ag), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. (Ref.1,2) These ITIMs interact with the SH2 domains of protein phosphatases such as SHP1. (Ref.3,4) Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. The effect of MHC class I expression is indirect, and can be mediated by interactions with class I-specific Ly49 inhibitory receptors. (Ref.1)Synonyms: C-type lectin domain family 15 member A, CLEC15A, ITIM-containing receptor MAFA-L, KLRG1, Killer cell lectin-like receptor subfamily G member 1, MAFA, MAFA-like receptor, MAFAL, Mast cell function-associated antigen
- 基因ID
- 50928
- UniProt
- O88713
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