-
- 抗原 See all KLRG1 抗体
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
-
适用
- 小鼠
-
宿主
-
Golden Syrian Hamster
-
克隆类型
- 单克隆
-
标记
- This KLRG1 antibody is conjugated to FITC
-
应用范围
- Flow Cytometry (FACS)
- 纯化方法
- This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
- 克隆位点
- 2F1
- 亚型
- IgG
-
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 57-119) antibody
KLRG1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 1-189) antibodyKLRG1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 60-195) antibodyKLRG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibodyKLRG1 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 2F1 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (FITC)KLRG1 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 2F1 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (PE)KLRG1 适用: 小鼠 FACS 宿主: Golden Syrian Hamster Monoclonal 2F1 PE
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (APC)KLRG1 适用: 小鼠 FACS 宿主: Golden Syrian Hamster Monoclonal 2F1 APC
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (violetFluor™ 450)KLRG1 适用: 小鼠 FACS 宿主: Golden Syrian Hamster Monoclonal 2F1 violetFluor™ 450
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 1-189) antibodyKLRG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (PE)KLRG1 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 2F1 PE
-
- 应用备注
- This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indi- cated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.
- 说明
-
0.5 mg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 2-8°C protected from light
- 有效期
- 12 months
-
- 抗原
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
- 别名
- KLRG1 (KLRG1 产品)
- 别名
- KLRG1 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, 2F1 antibody, CLEC15A antibody, MAFA-2F1 antibody, MAFA-LIKE antibody, killer cell lectin like receptor G1 antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, KLRG1 antibody, Klrg1 antibody
- 背景
- The 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025). The 2F1 antibody may be used as a phenotypic marker for KLRG1 in mouse, frequently in combination with Anti-Mouse CD127 antibody (clone A7R34), for identification of effector T cell populations.
- 基因ID
- 50928
- UniProt
- O88713
-
You are here:
