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TNFRSF8 抗体 (Extracellular Domain)

TNFRSF8 适用: 小鼠 FACS, Func 宿主: 仓鼠 Monoclonal mCD30-1 unconjugated
产品编号 ABIN370916
发货至: 中国
  • 抗原 See all TNFRSF8 抗体
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    抗原表位
    • 16
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    • 1
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    Extracellular Domain
    适用
    • 136
    • 27
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    • 16
    小鼠
    宿主
    • 90
    • 61
    • 10
    • 4
    • 1
    仓鼠
    克隆类型
    • 93
    • 71
    • 2
    单克隆
    标记
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    This TNFRSF8 antibody is un-conjugated
    应用范围
    • 103
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    • 57
    • 45
    • 37
    • 27
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    • 13
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    This antibody is specific to Murine CD30, Mr 52 kDa (core peptide).
    产品特性
    Synonyms: TNFRSF8, D1S166E, CD30L receptor, KI-1 antigen, Tumor necrosis factor receptorsuperfamily member 8, Lymphocyte activation antigen CD30
    纯化方法
    Purified
    免疫原
    Recombinant mouse CD30 extracellular domain-mouse IgG1 fusion protein. (Ref. 1)
    克隆位点
    MCD30-1
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF8 Primary Antibody
  • 应用备注
    Flow Cytometry: < / 3 μg/10^6 cells. Functional Assay: In vitro costimulation of T cells and NK cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    别名
    CD30 (TNFRSF8 产品)
    别名
    CD30 antibody, D1S166E antibody, Ki-1 antibody, Cd30 antibody, Ki antibody, TNFRSF8 antibody, TNF receptor superfamily member 8 antibody, tumor necrosis factor receptor superfamily, member 8 antibody, TNFRSF8 antibody, Tnfrsf8 antibody
    背景
    CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. (Ref.1,2) Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. (Ref.1) In anti-CD3e-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-gamma production. (Ref.1) While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.Synonyms: CD30L receptor, D1S166E, KI-1 antigen, Lymphocyte activation antigen CD30, TNFRSF8, Tumor necrosis factor receptor superfamily member 8
    基因ID
    21941
    UniProt
    Q60846
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