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GRP78 抗体 (C-Term)

HSPA5 适用: 大鼠, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN363672
发货至: 中国
  • 抗原 See all GRP78 (HSPA5) 抗体
    GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
    抗原表位
    • 26
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    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 600-654, C-Term
    适用
    • 184
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    • 1
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    大鼠, 小鼠
    宿主
    • 130
    • 89
    • 8
    • 3
    • 1
    • 1
    克隆类型
    • 134
    • 99
    多克隆
    标记
    • 98
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    This GRP78 antibody is un-conjugated
    应用范围
    • 218
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Reacts with rat and mouse 78 kDa GRP-78 protein
    交叉反应 (详细)
    Weakly cross reacts with human GRP-78.
    纯化方法
    Antigen affinity purified
    免疫原
    Synthetic peptide derived from C-term domain of the rat Grp78 protein. Within residues 600-654.
    Top Product
    Discover our top product HSPA5 Primary Antibody
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB0.5 μg/mL ICC/IF1:50

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.05 mg/mL
    缓冲液
    PBS, glycerol 30 % , Sodium azide 0.1 %
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    有效期
    6 months
  • 抗原
    GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
    别名
    78 kDa Glucose-Regulated Protein (GRP-78) (HSPA5 产品)
    别名
    GRP78 antibody, BiP antibody, GRP-78 antibody, grp78 antibody, hspa5a antibody, BIP antibody, MIF2 antibody, AL022860 antibody, AU019543 antibody, Bip antibody, D2Wsu141e antibody, D2Wsu17e antibody, Grp78 antibody, Hsce70 antibody, SEZ-7 antibody, Sez7 antibody, baffled antibody, mBiP antibody, cb865 antibody, fb60h09 antibody, fi36d04 antibody, wu:fb60h09 antibody, wu:fi36d04 antibody, zgc:55994 antibody, zgc:77606 antibody, 78 kDa glucose-regulated protein antibody, heat shock protein family A (Hsp70) member 5 antibody, BiP/GRP78 antibody, glucose-regulated protein 78 antibody, putative glucose-regulated protein 78 antibody, Hsp70 family ATPase KAR2 antibody, heat shock protein family A (Hsp70) member 5 S homeolog antibody, heat shock 70 kDa protein 5a antibody, heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) antibody, heat shock protein 5 antibody, heat shock protein family A member 5 antibody, CpipJ_CPIJ003550 antibody, HSPA5 antibody, grp78 antibody, LOC100533358 antibody, BiP/grp78 antibody, Tc00.1047053506585.40 antibody, Tb11.02.5450 antibody, Tb11.02.5500 antibody, LMJF_28_1200 antibody, KAR2 antibody, LOC100135840 antibody, hspa5.S antibody, hspa5 antibody, Hspa5 antibody
    背景
    Categorized as stress response proteins, BiPs play an important role in folding and assembly of nascent proteins and in scavenging of misfolded proteins in the endoplasmic reticulum lumen. Translation of BiP is directed by an internal ribosomal entry site (IRES) in the 5- nontranslated region of BiP mRNA. BiP IRES activity increases when cells are heat-stressed. GRP78 is also important in maintenance of cell homeostasis and the prevention of apoptosis. Levels of GRP78 protein are reduced in brains of Alzheimer's disease patients.
    基因ID
    25617
    途径
    Thyroid Hormone Synthesis, ER-Nucleus Signaling
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